SCHEMBL502621

SCHEMBL502621

Nc1ncnc2c1ncn2OP(=O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ENPP1 P22413 2/20 0.52
▸ ENPP3 O14638 1/20 0.50
▸ P2RY2 P41231 5/20 0.49
▸ P2RX1 P51575 3/20 0.49
▸ P2RX3 P56373 3/20 0.49
▸ P2RX2 Q9UBL9 2/20 0.49
▸ P2RY1 P47900 5/20 0.48
▸ P2RY11 Q96G91 1/20 0.48
▸ FGFR1 P11362 1/20 0.46
▸ SLC22A6 Q4U2R8 1/20 0.46
▸ P2RX4 Q99571 2/20 0.46
▸ SRC P12931 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ RNASEL Q05823 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1035726 0.99 ENPP1 (0.51) ENPP1ENPP3P2RY2P2RX1P2RX3
SCHEMBL8509835 0.97 ENPP1 (0.50) ENPP1ENPP3P2RY2P2RX1P2RX3
SCHEMBL27721221 0.88 FGFR1 (0.47) ENPP1ENPP3P2RY2P2RX1P2RX3
SCHEMBL283730 0.87 FGFR1 (0.51) ENPP1ENPP3P2RY2P2RY1P2RY11
SCHEMBL1074484 0.83 CDK1 (0.40) ENPP1ENPP3P2RY2P2RX1P2RX3
Acetone SCHEMBL28162073 0.82 CYP3A4 (0.47) ENPP1P2RY2P2RY1P2RY11FGFR1
Niacinamide SCHEMBL27733580 0.82 EGFR (0.52) ENPP1ENPP3P2RY2P2RX1P2RX3
SCHEMBL27903676 0.82 CYP3A4 (0.47) ENPP1ENPP3P2RY2P2RX1P2RX3
SCHEMBL5089696 0.81 ENPP1 (0.46) ENPP1ENPP3P2RY2P2RX1P2RX3
SCHEMBL28139965 0.80 FGFR1 (0.43) ENPP1ENPP3P2RY2P2RX1P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 506 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4596713-A1 DNA WITH ENHANCED RESISTANCE AGAINST EXONUCLEASES AND METHODS FOR THE PRODUCTION THEREOF 4basebio UK Ltd (GB) 2025-08-06 — — EP claimed
CN-119614709-A Detection method and application of whole genome 5-hydroxymethylcytosine 青岛科技大学 2025-03-14 — — CN claimed
WO-2024250923-A1 CHEMICALLY MODIFIED NUCLEOSIDE, CHEMICALLY MODIFIED NUCLEOSIDE TRIPHOSPHATE AND USE THEREOF 中国科学院深圳先进技术研究院 2024-12-12 — — WO claimed
US-20240350027-A1 Methods and Apparatus for Benchtop Metabolite Profiling in Situ VIBO HEALTH INC (US) 2024-10-24 — — US claimed
EP-4436358-A1 PROCESSES AND SYSTEMS FOR INCREASING DRY MATTER IN HYDROPONICALLY GROWN CELLULOSIC MATERIALS Hydrogreen, Inc. (CA) 2024-10-02 — — EP claimed
WO-2023096635-A1 PROCESSES AND SYSTEMS FOR INCREASING DRY MATTER IN HYDROPONICALLY GROWN CELLULOSIC MATERIALS HYDROGREEN, INC (CA) 2023-06-01 — — WO claimed
US-20230157229-A1 PROCESSES AND SYSTEMS FOR INCREASING DRY MATTER IN HYDROPONICALLY GROWN CELLULOSIC MATERIALS Hydrogreen, Inc. (CA) 2023-05-25 — — US claimed
CN-111505284-B Test paper strip and sensor for detecting novel coronavirus SARS-CoV-2, and preparation and application thereof 中国科学院重庆绿色智能技术研究院 2023-05-02 — — CN claimed
WO-2023022997-A1 METHODS AND APPARATUS FOR BENCHTOP METABOLITE PROFILING IN SITU ViBo Health Inc. (US) 2023-02-23 — — WO claimed
US-20220275028-A1 Systems, Methods And Compositions For Recombinant In Vitro Transcription And Translation Utilizing Thermophilic Proteins NATURE'S TOOLBOX, INC. 2022-09-01 — — US claimed
US-7022494-B2 Detection of potassium ions using ion-sensitive enzymes GENERAL ATOMICS (US) 2006-04-04 — — US claimed
US-20050266508-A1 Detection of potassium ions using ion-sensitive enzymes DIAZYME LABORATORIES, INC. 2005-12-01 — — US claimed
WO-2005029038-A2 DETECTION OF POTASSIUM IONS USING ION-SENSITIVE ENZYMES GENERAL ATOMICS (US) 2005-03-31 — — WO claimed
US-20050069970-A1 Detection of potassium ions using ion-sensitive enzymes GENERAL ATOMICS 2005-03-31 — — US claimed
US-20030212006-A1 Method for reducing free radical formation in healthy individuals undergoing hypoxic exercise and medical conditions with increased oxygen free radicals BIONERGY, INC. 2003-11-13 — — US claimed
EP-1032700-A1 SEPARATION OF NUCLEIC ACIDS BY ANTIBODIES TO HALOGENATED NUCLEOTIDES New York Medical College (US) 2000-09-06 — — EP claimed
CN-1049246-C Method for preparing powder type culture-medium of animal cell KANGDA AMINO ACID FASTORY SHAN (CN) 2000-02-09 — — CN claimed
WO-1999006592-A9 SEPARATION OF NUCLEIC ACIDS BY ANTIBODIES TO HALOGENATED NUCLEOTIDES NEW YORK MEDICAL COLLEGE (US) 1999-05-06 — — WO claimed
WO-1999006592-A1 SEPARATION OF NUCLEIC ACIDS BY ANTIBODIES TO HALOGENATED NUCLEOTIDES NEW YORK MEDICAL COLLEGE (US) 1999-02-11 — — WO claimed
EP-0147713-A2 Enzymatic ATP and FMN assay Miles Italiana SpA (IT) 1985-07-10 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220275028-A1 Systems, Methods And Compositions For Recombinant In Vitro Transcription And Translation Utilizing Thermophilic Proteins MRPL21, RNGTT, MRPS23 ENPP1 2948/4885ENPP3 2055/4885P2RY2 4688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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