Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17224383 | 0.97 | GPR3 (0.46) | GPR3CYP1A2CYP2C19KDM4EL3MBTL1 | |
| SCHEMBL36244 | 0.97 | GPR3 (0.46) | GPR3CYP1A2CYP2C19KDM4EL3MBTL1 | |
| SCHEMBL29352713 | 0.97 | GPR3 (0.46) | GPR3CYP1A2CYP2C19KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL15638077 | 0.95 | GPR3 (0.44) | GPR3CYP1A2CYP2C19KDM4EL3MBTL1 | |
| Charcoal, Activated SCHEMBL546897 | 0.95 | GPR3 (0.44) | GPR3CYP1A2CYP2C19KDM4EL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL11656972 | 0.95 | GPR3 (0.44) | GPR3CYP1A2CYP2C19KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11276947 | 0.95 | GPR3 (0.44) | GPR3CYP1A2CYP2C19KDM4EL3MBTL1 | |
| Ethylene SCHEMBL9860373 | 0.95 | GPR3 (0.44) | GPR3CYP1A2CYP2C19KDM4EL3MBTL1 | |
| SCHEMBL17712323 | 0.91 | GPR3 (0.41) | GPR3CYP1A2CYP2C19KDM4EL3MBTL1 | |
| SCHEMBL9615928 | 0.91 | GPR3 (0.41) | GPR3CYP1A2CYP2C19KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62090662-A | — | — | None | — | — | JP | disclosed |
| JP-S6290662-A | LAMINATION TYPE ELECTROPHOTOGRAPHIC SENSITIVE BODY | MATSUSHITA ELECTRIC IND CO LTD | 1987-04-25 | — | — | JP | disclosed |
| US-4362797-A | Electrophotographc process to release trapped charges by charging and ultraviolet exposure | OLYMPUS OPTICAL COMPANY LIMITED (JP) | 1982-12-07 | — | — | US | disclosed |
| US-4264193-A | Image converting and projecting method and apparatus for carrying out the same | MATSUSHITA ELECTRIC INDUSTRIAL CO. LTD (JP) | 1981-04-28 | — | — | US | disclosed |