SCHEMBL1074553

SCHEMBL1074553

CC(=CC1(C=C(C)C(=O)O)CO1)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.32
AKR1C3 P42330 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4278528 0.89
SCHEMBL16499876 0.78 CD81 (0.32) PTGS1AKR1C3
SCHEMBL16499878 0.78 CD81 (0.32) PTGS1AKR1C3
SCHEMBL726326 0.75 CD81 (0.30)
SCHEMBL5713049 0.73 PTGS1 (0.31) PTGS1AKR1C3
SCHEMBL28109278 0.73 AKR1C3 (0.32) AKR1C3
SCHEMBL7714153 0.72
SCHEMBL3392711 0.70
SCHEMBL782181 0.70
SCHEMBL3288566 0.70 FFAR3 (0.36) PTGS1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2139931-B1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING PHENYLENE-SILOXANE MACROMERS ALCON INC (CH) 2011-01-19 EP claimed
US-7847046-B2 Ophthalmic and otorhinolaryngological device materials containing phenylene-siloxane macromers ALCON, INC. (CH) 2010-12-07 US claimed
EP-1891466-B1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON INC (CH) 2010-09-15 EP claimed
EP-1891127-B1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON INC (CH) 2010-03-24 EP claimed
US-7652076-B2 a self-reinforced crosslinked acrylate or methacrylate copolymer; soft, high refractive index, high strength, intraocular lenses, contact lenses, corneal rings, otological ventilation tubes, nasal implants ALCON, INC. (CH) 2010-01-26 US claimed
EP-2139931-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING PHENYLENE-SILOXANE MACROMERS Alcon, Inc. (CH) 2010-01-06 EP claimed
US-20090198327-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON INC. (CH) 2009-08-06 US claimed
WO-2008134672-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING PHENYLENE-SILOXANE MACROMERS ALCON, INC. (CH) 2008-11-06 WO claimed
US-20080269418-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING PHENYLENE-SILOXANE MACROMERS ALCON RESEARCH, LTD. (US) 2008-10-30 US claimed
EP-1891127-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON INC. (CH) 2008-02-27 EP claimed
EP-1891466-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON INC. (CH) 2008-02-27 EP claimed
WO-2006138188-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON, INC. (CH) 2006-12-28 WO claimed
WO-2006138213-A1 OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS ALCON, INC. (CH) 2006-12-28 WO claimed
US-20060282163-A1 Ophthalmic and otorhinolaryngological device materials ALCON, INC. 2006-12-14 US claimed
US-20060281888-A1 Ophthalmic and otorhinolaryngological device materials ALCON, INC. 2006-12-14 US claimed
EP-0417624-B1 Electrochromic window with polymer layer PPG INDUSTRIES INC (US) 1997-04-02 EP claimed
EP-3638705-B1 INTRAOCULAR LENS COMPOSITIONS ALCON INC (CH) 2024-02-28 EP disclosed
US-11642217-B2 Intraocular lens compositions ALCON INC. (CH) 2023-05-09 US disclosed
EP-0078169-B1 POLYMERISABLE MONOMERS, POLYMER DISPERSIONS AND DERIVED PAINTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-09-28 EP disclosed
EP-0078169-A2 Polymerisable monomers, polymer dispersions and derived paints IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-05-04 EP disclosed