Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 11/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | MTOR | P42345 | 3/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.75 |
| ▸ | THPO | P40225 | 3/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | BLM | P54132 | 3/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.74 |
| ▸ | DRD2 | P14416 | 7/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | DRD5 | P21918 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10747243 | 0.99 | DRD1 (0.76) | DRD1KDM4EMAPTMTORCYP2D6 | |
| Hydrochloric Acid SCHEMBL10345839 | 0.88 | DRD1 (0.74) | DRD1KDM4EMAPTMTORCYP2D6 | |
| SCHEMBL7390591 | 0.86 | DRD1 (1.00) | DRD1KDM4EMAPTMTORCYP2D6 | |
| Hydrochloric Acid SCHEMBL7203243 | 0.85 | DRD1 (1.00) | DRD1KDM4EMAPTMTORCYP2D6 | |
| Bromide SCHEMBL11288446 | 0.85 | KDM4E (1.00) | DRD1KDM4EMAPTMTORCYP2D6 | |
| Bromide SCHEMBL10748879 | 0.81 | KDM4E (0.74) | DRD1KDM4EMAPTMTORCYP2D6 | |
| SCHEMBL10564217 | 0.78 | DRD1 (0.43) | DRD1KDM4EMAPTMTORCYP2D6 | |
| Hydrochloric Acid SCHEMBL10351379 | 0.77 | DRD1 (0.44) | DRD1KDM4EMAPTMTORCYP2D6 | |
| SCHEMBL18085055 | 0.76 | DRD1 (0.73) | DRD1KDM4EMAPTMTORCYP2D6 | |
| SCHEMBL14510732 | 0.76 | DRD1 (0.82) | DRD1KDM4EMAPTMTORCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244088-A2 | 1-Phenyl-3-benzazepine compounds and medicaments containing these compounds for treating gastrointestinal motility disorders | SMITHKLINE BEECHAM CORPORATION (US) | 1987-11-04 | — | — | EP | disclosed |