SCHEMBL10746005

SCHEMBL10746005

Fc1nc(F)c(F)c(C(F)(F)F)n1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM5B Q9UGL1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12788225 0.76 KDM5B (0.32) KDM5B
SCHEMBL10737432 0.75 KDM5B (0.30) KDM5B
SCHEMBL10583927 0.75 ENPP3 (0.33)
SCHEMBL9483455 0.75 ENPP3 (0.30)
SCHEMBL10847860 0.75 KDM5B (0.30) KDM5B
SCHEMBL5675318 0.73 MEN1 (0.33)
SCHEMBL24228115 0.70 KDM5B (0.30) KDM5B
SCHEMBL9435934 0.69
SCHEMBL18550583 0.67 KDM5B (0.33) KDM5B
SCHEMBL24228127 0.65 KDM5B (0.32) KDM5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4716229-A New pyrimidines and a process for the preparation of pyrimidines BAYER AKTIENGESELLSCHAFT (DE) 1987-12-29 US disclosed
EP-0133663-B1 PYRIMIDINES AND A PROCESS FOR THE PREPARATION OF PYRIMIDINES BAYER AG (DE) 1987-04-08 EP disclosed
EP-0133663-A1 Pyrimidines and a process for the preparation of pyrimidines BAYER AG (DE) 1985-03-06 EP disclosed