Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 7/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 6/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28226119 | 0.81 | CFTR (0.49) | L3MBTL1CFTRMEN1KMT2ADUSP3 | |
| SCHEMBL13280707 | 0.79 | CFTR (0.64) | CFTRMEN1KMT2ATMPRSS4P2RX1 | |
| SCHEMBL10455842 | 0.78 | MEN1 (0.44) | MEN1KMT2ATMPRSS4P2RX1AKT1 | |
| SCHEMBL10512115 | 0.77 | AR (0.42) | MEN1KMT2ADUSP3TMPRSS4P2RX1 | |
| SCHEMBL10373446 | 0.74 | CSNK2A1 (0.52) | MEN1KMT2ADUSP3TMPRSS4P2RX1 | |
| SCHEMBL21367459 | 0.73 | CFTR (0.49) | CFTRMEN1KMT2ATMPRSS4P2RX1 | |
| SCHEMBL17141748 | 0.73 | MEN1 (0.43) | CFTRMEN1KMT2ATMPRSS4P2RX1 | |
| SCHEMBL11631790 | 0.73 | CA1 (0.50) | MEN1KMT2ATMPRSS4P2RX1P2RX4 | |
| SCHEMBL30062195 | 0.73 | CES2 (0.52) | L3MBTL1MEN1KMT2ATMPRSS4P2RX1 | |
| SCHEMBL320481 | 0.73 | CES2 (0.52) | L3MBTL1MEN1KMT2ATMPRSS4P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663344-A | ANTIPYRETICS, ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1987-05-05 | — | — | US | disclosed |