Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10746515 | 1.00 | CYP2C9 (0.51) | CYP2C9POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL10705801 | 0.92 | FFAR1 (0.53) | CYP2C9POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL10705795 | 0.92 | FFAR1 (0.53) | CYP2C9POLBMAPTKDM4EALDH1A1 | |
| Anisole SCHEMBL28132815 | 0.85 | FFAR1 (0.55) | CYP2C9POLBMAPTFFAR1TSHR | |
| SCHEMBL11937090 | 0.84 | FFAR1 (0.44) | CYP2C9POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL6938802 | 0.84 | FFAR1 (0.50) | FFAR1ESR2AAK1CYP3A4ADRB3 | |
| SCHEMBL7686129 | 0.84 | FFAR1 (0.50) | FFAR1ESR2AAK1CYP3A4ADRB3 | |
| SCHEMBL801370 | 0.83 | HTT (0.47) | CYP2C9POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL20851317 | 0.82 | HPGD (0.70) | CYP2C9POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL21386579 | 0.81 | MMP2 (0.57) | KDM4EALDH1A1HPGDFFAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4676925-A | Liquid crystalline biphenyl derivatives and mixtures thereof | CHISSO CORPORATION (JP) | 1987-06-30 | — | — | US | disclosed |
| EP-0131373-B1 | LIQUID CRYSTALLINE BIPHENYL DERIVATIVES AND MIXTURES THEREOF | Chisso Corporation (JP) | 1986-12-30 | — | — | EP | disclosed |
| US-4614609-A | FERROELECTRICITY; DISPLAY ELEMENTS | CHISSO CORPORATION (JP) | 1986-09-30 | — | — | US | disclosed |
| EP-0131373-A1 | Liquid crystalline biphenyl derivatives and mixtures thereof | Chisso Corporation (JP) | 1985-01-16 | — | — | EP | disclosed |