Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.61 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.61 |
| ▸ | RARB | P10826 | 3/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.56 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899214 | 1.00 | TP53 (0.67) | TP53GAARAB9ANPC1LMNA | |
| SCHEMBL7889286 | 1.00 | TP53 (0.67) | TP53GAARAB9ANPC1LMNA | |
| SCHEMBL15019645 | 1.00 | TP53 (0.67) | TP53GAARAB9ANPC1LMNA | |
| SCHEMBL7899200 | 0.95 | RAB9A (0.64) | TP53GAARAB9ANPC1LMNA | |
| SCHEMBL7896219 | 0.87 | GAA (0.54) | TP53GAARAB9ANPC1LMNA | |
| Benzene SCHEMBL28017867 | 0.84 | MEN1 (0.52) | TP53GAARAB9ANPC1LMNA | |
| SCHEMBL19723267 | 0.83 | TP53 (0.73) | TP53GAARAB9ANPC1LMNA | |
| SCHEMBL7455430 | 0.83 | TP53 (0.73) | TP53GAARAB9ANPC1LMNA | |
| SCHEMBL4652240 | 0.83 | TP53 (0.73) | TP53GAARAB9ANPC1LMNA | |
| SCHEMBL9649959 | 0.83 | PRMT1 (0.83) | TP53GAARAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4715984-A | DIELECTRICS FOR ELECTROOPTICAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-12-29 | — | — | US | disclosed |