Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 6/20 | 0.32 |
| ▸ | CTSK | P43235 | 6/20 | 0.32 |
| ▸ | CTSL | P07711 | 4/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 5/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402765 | 1.00 | ELANE (0.35) | ELANEPOLBCTSSCTSKCTSL | |
| SCHEMBL10402846 | 1.00 | ELANE (0.35) | ELANEPOLBCTSSCTSKCTSL | |
| SCHEMBL9358907 | 0.88 | POLB (0.38) | POLBCTSSCTSKCTSLMEN1 | |
| SCHEMBL8104148 | 0.75 | POLB (0.36) | POLBCTSSCTSKCTSLCTSB | |
| SCHEMBL7187098 | 0.75 | POLB (0.36) | POLBCTSSCTSKCTSLCTSB | |
| SCHEMBL7187100 | 0.75 | POLB (0.36) | POLBCTSSCTSKCTSLCTSB | |
| SCHEMBL8104152 | 0.75 | POLB (0.36) | POLBCTSSCTSKCTSLCTSB | |
| SCHEMBL9175389 | 0.75 | POLB (0.36) | POLBCTSSCTSKCTSLCTSB | |
| SCHEMBL3807151 | 0.74 | MAPT (0.36) | — | |
| SCHEMBL10585129 | 0.74 | MAPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4692442-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
| US-4203896-A | WITH MERCURIC ACETATE AND ACETIC ACID, ACIDIC HYDROLYSIS OF N-PROPENYL GROUP | ELI LILLY AND COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4144232-A | Substituted azetidin-2-one antibiotics | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |