SCHEMBL9358907

SCHEMBL9358907

CC(=O)OC1NC(=O)C1OC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.38
CTSK P43235 8/20 0.33
CTSS P25774 7/20 0.33
CTSL P07711 4/20 0.33
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
CTSB P07858 6/20 0.32
PRKD3 O94806 2/20 0.31
PRKCG P05129 2/20 0.31
PRKCB P05771 2/20 0.31
PRKCA P17252 2/20 0.31
PRKCH P24723 2/20 0.31
PRKCE Q02156 2/20 0.31
PRKCQ Q04759 2/20 0.31
PRKCD Q05655 2/20 0.31
PRKD1 Q15139 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10402846 0.88 ELANE (0.35) POLBCTSKCTSSCTSLMEN1
SCHEMBL10747693 0.88 ELANE (0.35) POLBCTSKCTSSCTSLMEN1
SCHEMBL10402765 0.88 ELANE (0.35) POLBCTSKCTSSCTSLMEN1
SCHEMBL7187098 0.78 POLB (0.36) POLBCTSKCTSSCTSLCTSB
SCHEMBL8104152 0.78 POLB (0.36) POLBCTSKCTSSCTSLCTSB
SCHEMBL8104148 0.78 POLB (0.36) POLBCTSKCTSSCTSLCTSB
SCHEMBL7187100 0.78 POLB (0.36) POLBCTSKCTSSCTSLCTSB
SCHEMBL9175389 0.78 POLB (0.36) POLBCTSKCTSSCTSLCTSB
SCHEMBL3807151 0.77 MAPT (0.36)
SCHEMBL10585129 0.77 MAPT (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0371875-B1 Process for preparing 4-acetoxyazetidinones TAKASAGO PERFUMERY CO LTD (JP) 1994-12-28 EP disclosed
EP-0371875-A3 PROCESS FOR PREPARING 4-ACETOXYAZETIDINONES Takasago International Corporation (JP) 1991-09-25 EP disclosed
EP-0371875-A2 Process for preparing 4-acetoxyazetidinones Takasago International Corporation (JP) 1990-06-06 EP disclosed