Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | PMM2 | O15305 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYBB | P04839 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5916963 | 0.81 | METAP2 (0.54) | ALDH1A1MAPTHTTMETAP2KDM4E | |
| SCHEMBL10501640 | 0.76 | METAP2 (0.37) | ALDH1A1MAPTHTTMETAP2KDM4E | |
| SCHEMBL10501870 | 0.74 | METAP2 (0.39) | ALDH1A1MAPTHTTMETAP2KDM4E | |
| SCHEMBL10747582 | 0.73 | METAP2 (0.40) | ALDH1A1MAPTHTTMETAP2KDM4E | |
| SCHEMBL10747007 | 0.73 | METAP2 (0.38) | ALDH1A1MAPTHTTMETAP2KDM4E | |
| SCHEMBL10501733 | 0.73 | METAP2 (0.36) | ALDH1A1MAPTHTTMETAP2KDM4E | |
| SCHEMBL10501392 | 0.73 | METAP2 (0.34) | ALDH1A1MAPTHTTMETAP2KDM4E | |
| SCHEMBL10503039 | 0.73 | METAP2 (0.41) | ALDH1A1MAPTHTTMETAP2KDM4E | |
| SCHEMBL10501737 | 0.72 | METAP2 (0.41) | ALDH1A1MAPTHTTMETAP2KDM4E | |
| SCHEMBL10502616 | 0.72 | METAP2 (0.46) | ALDH1A1MAPTHTTMETAP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |