SCHEMBL10748830

SCHEMBL10748830

CC1=CCC(C)(C)C=CCC(C)(O)CCC1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.40
GLI1 P08151 1/20 0.40
GLI2 P10070 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10748823 1.00 CYP3A4 (0.40) CYP3A4GLI1GLI2
SCHEMBL10748820 1.00 CYP3A4 (0.40) CYP3A4GLI1GLI2
SCHEMBL30034984 1.00 CYP3A4 (0.40) CYP3A4GLI1GLI2
SCHEMBL10750874 0.78 GLI1 (0.38) CYP3A4GLI1GLI2
SCHEMBL10750869 0.78 GLI1 (0.38) CYP3A4GLI1GLI2
SCHEMBL22516443 0.72
SCHEMBL3683014 0.71 TRPA1 (0.33) CYP3A4
SCHEMBL3683011 0.71 TRPA1 (0.33) CYP3A4
SCHEMBL3438794 0.70 CYP3A4 (0.40) CYP3A4GLI1GLI2
SCHEMBL79972 0.70 CYP3A4 (0.40) CYP3A4GLI1GLI2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62292740-A None JP disclosed
JP-S62292740-A 1,5,5,8-TETRAMETHYL-1-METHOXY-3,7-CYCLOUNDECADIENE KIRIN BREWERY CO LTD 1987-12-19 JP disclosed