Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | DBH | P09172 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11500142 | 0.88 | GAA (0.44) | TDP1SMN1; SMN2HTTGAADBH | |
| SCHEMBL11566163 | 0.86 | TDP1 (0.52) | TDP1HTTGAAALDH1A1HPGD | |
| SCHEMBL6277589 | 0.86 | TDP1 (0.52) | TDP1HTTGAAALDH1A1HPGD | |
| SCHEMBL7389037 | 0.83 | TDP1 (0.45) | TDP1SMN1; SMN2HTTGAAALDH1A1 | |
| SCHEMBL11500225 | 0.76 | HTT (0.40) | TDP1SMN1; SMN2HTTGAAALDH1A1 | |
| SCHEMBL11653951 | 0.76 | GAA (0.44) | TDP1SMN1; SMN2HTTGAAALDH1A1 | |
| SCHEMBL12595185 | 0.75 | MAPT (0.60) | TDP1SMN1; SMN2HTTGAAALDH1A1 | |
| SCHEMBL10737116 | 0.73 | POLB (0.47) | TDP1GAAALDH1A1HPGDALOX15 | |
| SCHEMBL11651079 | 0.72 | GAA (0.47) | TDP1HTTGAAALDH1A1HPGD | |
| SCHEMBL30588975 | 0.72 | IDO1 (0.55) | TDP1SMN1; SMN2HTTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4672101-A | Polyepoxy aromatic hydantoins | THE DOW CHEMICAL COMPANY (US) | 1987-06-09 | — | — | US | disclosed |