Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566163 | 1.00 | TDP1 (0.52) | TDP1HTTGAAMAPTTSHR | |
| SCHEMBL10749005 | 0.86 | TDP1 (0.42) | TDP1HTTGAAMAPTTSHR | |
| SCHEMBL7389037 | 0.83 | TDP1 (0.45) | TDP1HTTGAAMAPTTSHR | |
| SCHEMBL11653951 | 0.79 | GAA (0.44) | TDP1HTTGAAMAPTALDH1A1 | |
| SCHEMBL11651079 | 0.79 | GAA (0.47) | TDP1HTTGAAMAPTALDH1A1 | |
| SCHEMBL11645287 | 0.78 | TDP1 (0.44) | TDP1HTTGAAMAPTTSHR | |
| SCHEMBL10575685 | 0.78 | GSK3B (0.51) | TDP1GAAMAPTALDH1A1KMT2A | |
| SCHEMBL10656824 | 0.78 | GSK3B (0.51) | TDP1GAAMAPTALDH1A1KMT2A | |
| SCHEMBL8922115 | 0.78 | GSK3B (0.51) | TDP1GAAMAPTALDH1A1KMT2A | |
| SCHEMBL11652329 | 0.78 | GAA (0.57) | TDP1GAAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111847446-B | Aza-hybridized mesoporous carbon and preparation method thereof | 天津市职业大学 | 2023-05-26 | — | — | CN | claimed |
| CN-218296678-U | Oven steam waste heat use system is used in production of hydroxybenzene hydantoin | 内蒙古天宇达生物科技有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-111847446-A | Nitrogen-hybridized mesoporous carbon and preparation method thereof | 天津市职业大学 | 2020-10-30 | — | — | CN | claimed |
| WO-1991009020-A2 | PRODUCTION OF 5-(4'-HYDROXYPHENYL)HYDANTOIN AND D-p-HYDROXYPHENYLGLYCINE FROM 4-HYDROXYACETOPHENONE | HOECHST CELANESE CORPORATION (US) | 1991-06-27 | — | — | WO | claimed |
| US-4094741-A | CULTURES, ASYMMETRIC HYDROLYSIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1978-06-13 | — | — | US | claimed |
| JP-4364150-A | — | — | None | — | — | JP | disclosed |
| CN-111847446-B | Aza-hybridized mesoporous carbon and preparation method thereof | 天津市职业大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-218296678-U | Oven steam waste heat use system is used in production of hydroxybenzene hydantoin | 内蒙古天宇达生物科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-111847446-A | Nitrogen-hybridized mesoporous carbon and preparation method thereof | 天津市职业大学 | 2020-10-30 | — | — | CN | disclosed |
| CN-110981811-A | Preparation method of p-hydroxy-phenyl-hydantoin | 合肥利夫生物科技有限公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-101230123-B | Comprehensive utilization method for byproduct of p-hydroxybenzene hydantoin production | TIANJIN PROFESSIONAL COLLEGE | 2010-06-09 | — | — | CN | disclosed |
| CN-101230123-A | Comprehensive utilization method for byproduct of p-hydroxybenzene hydantoin production | TIANJIN PROFESSIONAL COLLEGE (CN) | 2008-07-30 | — | — | CN | disclosed |
| JP-H04364150-A | FORMATION OF HYDROXYAROMATIC KETOACETAL FROM HYDROXYAROMATIC METHYLKETONE, AND PREPARARION OF 5-(4'-HYDROXYPHENYL)HYDANTOIN AND D-PARA-HYDROXYPHENYLGLYCINE FROM 4-HYDROXYACETOPHENONE | HOECHST CELANESE CORP | 1992-12-16 | — | — | JP | disclosed |
| US-5120855-A | Formation of hydroxyaromatic ketoacetal from a hydroxyaromatic methylketone and production of 5-(4'-hydroxyphenyl)hydantoin and Dp-hydroxyphenylglycine from 4-hydroxyacetophenone | HOECHST CELANESE CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0437058-A1 | Formation of hydroxyaromatic ketoacetal from an hydroxyaromatic methylketone and production of 5-(4'-hydroxyphenyl)hydantoin and D-p-hydroxyphenylglycine from 4-hydroxyacetophenone | HOECHST CELANESE CORPORATION (US) | 1991-07-17 | — | — | EP | disclosed |
| US-4230869-A | REACTING PHENOL, UREA AND GLYCOLIC ACID | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1980-10-28 | — | — | US | disclosed |
| EP-0001319-A1 | Process for the preparation of hydroxyphenyl hydantoin and of hydroxyphenyl glycine, and compounds thus obtained | BEECHAM GROUP PLC (GB) | 1979-04-04 | — | — | EP | disclosed |
| US-4094741-A | CULTURES, ASYMMETRIC HYDROLYSIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1978-06-13 | — | — | US | disclosed |
| US-3993665-A | 3-Amidocoumaranones | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |
| US-3993666-A | Coumaranedione-3-monoximes | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |