Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10501985 | 0.87 | GAA (0.38) | KAT2BKDM4EALDH1A1EP300MAT2A | |
| SCHEMBL10747318 | 0.82 | KDM4E (0.32) | METAP2KDM4EBRD4LMNAHSP90AA1 | |
| SCHEMBL10502358 | 0.78 | METAP2 (0.51) | METAP2KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL10745150 | 0.73 | METAP2 (0.45) | METAP2MAT2A | |
| SCHEMBL10748041 | 0.72 | METAP2 (0.38) | KAT2BMETAP2KDM4ELMNAMAPT | |
| SCHEMBL10748298 | 0.71 | METAP2 (0.46) | KAT2BMETAP2KDM4EALDH1A1 | |
| SCHEMBL5916517 | 0.71 | GAA (0.42) | KDM4EMAPTALDH1A1 | |
| SCHEMBL10746363 | 0.71 | NQO2 (0.36) | KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL10745932 | 0.70 | METAP2 (0.45) | METAP2KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL10501949 | 0.70 | GAA (0.34) | KDM4EALDH1A1MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |