Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775931 | 0.76 | FFAR3 (0.32) | GLSHTT | |
| SCHEMBL31135782 | 0.67 | FFAR3 (0.33) | HTTALDH1A1 | |
| SCHEMBL12409412 | 0.64 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL29109148 | 0.64 | HTT (0.42) | HTTALDH1A1 | |
| SCHEMBL1446029 | 0.64 | HTT (0.38) | HTTALDH1A1 | |
| SCHEMBL9613245 | 0.64 | — | — | |
| SCHEMBL15461386 | 0.63 | MAPK1 (0.38) | GLSALDH1A1 | |
| SCHEMBL16887587 | 0.62 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL7991761 | 0.62 | — | — | |
| SCHEMBL11607516 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4656263-A | 6-β-substituted penicillanic acid compound free of the 6-α-epimer | PFIZER INC. (US) | 1987-04-07 | — | — | US | disclosed |
| US-4518530-A | 6-β-Substituted penicillanic acids as β-lactamase inhibitors | PFIZER INC. (US) | 1985-05-21 | — | — | US | disclosed |
| US-4517126-A | Penicillanic acid derivative | PFIZER INC. (US) | 1985-05-14 | — | — | US | disclosed |