Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27828815 | 0.83 | TLR8 (0.64) | TLR8KMT2ALMNAMAPTNCF1 | |
| SCHEMBL27932675 | 0.82 | HTT (0.63) | ALDH1A1KDM4EKMT2AGAAHPGD | |
| SCHEMBL27894524 | 0.81 | KMT2A (0.51) | TLR8ALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL240664 | 0.81 | NQO2 (0.57) | TLR8ALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL5192732 | 0.80 | KMT2A (0.58) | TLR8ALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL29102436 | 0.80 | CYP2A6 (0.47) | TLR8ALDH1A1GLAMAPTTSHR | |
| SCHEMBL29919659 | 0.80 | CYP2A6 (0.47) | TLR8ALDH1A1GLAMAPTTSHR | |
| SCHEMBL10777924 | 0.80 | ALDH1A1 (0.50) | TLR8ALDH1A1KDM4EKMT2AGAA | |
| Hydrochloric Acid SCHEMBL15271481 | 0.79 | NQO2 (0.56) | TLR8ALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL2314941 | 0.79 | ALDH1A1 (0.47) | TLR8ALDH1A1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104281006-B | Radiation-ray sensitive composition | 三菱瓦斯化学株式会社 | 2019-01-22 | — | — | CN | disclosed |
| US-4696936-A | 3,6-bis (substituted) acridine N-oxides and N,N-dioxides and methods of restoring, stimulating or enhancing the immune system with them | AMERICAN CYANAMID COMPANY (US) | 1987-09-29 | — | — | US | disclosed |
| EP-0139526-A2 | An insolubilized stable specific binding protein | WARNER-LAMBERT COMPANY (US) | 1985-05-02 | — | — | EP | disclosed |
| EP-0115681-A1 | Process for producing a solid phase immunoassay | WARNER-LAMBERT COMPANY (US) | 1984-08-15 | — | — | EP | disclosed |