Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | GRK5 | P34947 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10754320 | 0.87 | MEN1 (0.52) | L3MBTL1SMN1; SMN2ALDH1A1MAPK1MEN1 | |
| SCHEMBL10751239 | 0.86 | MAPT (0.49) | L3MBTL1ALDH1A1MAPK1MAPTPOLB | |
| SCHEMBL10751994 | 0.79 | TSHR (0.54) | L3MBTL1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL10754799 | 0.79 | TPMT (0.39) | L3MBTL1MEN1KMT2AHPGDMAPT | |
| SCHEMBL10755218 | 0.78 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL10751516 | 0.78 | TSHR (0.42) | CHEK1DAPK3GRK5LIMK1SMN1; SMN2 | |
| SCHEMBL10752526 | 0.76 | MAPT (0.40) | L3MBTL1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL10751293 | 0.74 | KDM4E (0.45) | CYP3A4ALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL10751487 | 0.74 | POLB (0.42) | CYP3A4ALDH1A1KMT2AHPGDMAPT | |
| SCHEMBL10750105 | 0.73 | HPGD (0.46) | L3MBTL1SMN1; SMN2CYP3A4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687858-A | HERBICIDES | SANKYO COMPANY LIMITED (JP) | 1987-08-18 | — | — | US | disclosed |
| US-4508910-A | Herbicidal 4-benzoyl-5-hydroxy-pyrazales | SANKYO COMPANY LTD. (JP) | 1985-04-02 | — | — | US | disclosed |
| US-4414392-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY, LTD. (JP) | 1983-11-08 | — | — | US | disclosed |
| US-4301293-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY LTD. (JP) | 1981-11-17 | — | — | US | disclosed |
| US-4146726-A | HERBICIDES | SANKYO COMPANY LIMITED (JP) | 1979-03-27 | — | — | US | disclosed |
| US-4063925-A | Herbicidal compositions | SANKYO COMPANY LIMITED (JA) | 1977-12-20 | — | — | US | disclosed |