Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 9/20 | 0.40 |
| ▸ | MAOB | P27338 | 9/20 | 0.40 |
| ▸ | KDM1A | O60341 | 8/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10736010 | 1.00 | MEN1 (0.47) | MEN1KMT2ACHRNA7MAOAMAOB | |
| SCHEMBL10751693 | 1.00 | MEN1 (0.47) | MEN1KMT2ACHRNA7MAOAMAOB | |
| SCHEMBL418730 | 1.00 | MEN1 (0.47) | MEN1KMT2ACHRNA7MAOAMAOB | |
| SCHEMBL395631 | 0.96 | MEN1 (0.47) | MEN1KMT2ACHRNA7MAOAMAOB | |
| SCHEMBL13735039 | 0.96 | MEN1 (0.47) | MEN1KMT2ACHRNA7MAOAMAOB | |
| SCHEMBL6389916 | 0.88 | MEN1 (0.44) | MEN1KMT2ACHRNA7MAOAMAOB | |
| SCHEMBL28843512 | 0.88 | CHRNA7 (0.41) | MEN1KMT2ACHRNA7MAOAMAOB | |
| SCHEMBL20547603 | 0.83 | MAOB (0.45) | MEN1KMT2ACHRNA7MAOAMAOB | |
| SCHEMBL6389922 | 0.81 | HDAC4 (0.42) | MEN1KMT2ACHRNA7MAOAMAOB | |
| SCHEMBL27470692 | 0.81 | MEN1 (0.39) | MEN1KMT2ACHRNA7MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4705807-A | NERVOUS SYSTEM DISORDERS | LILLY INDUSTRIES LIMITED (GB) | 1987-11-10 | — | — | US | disclosed |