SCHEMBL27470692

SCHEMBL27470692

[CH]1CCC(C2CCCCC2)C(c2ccccc2)C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CHRNA7 P36544 1/20 0.37
MAOB P27338 11/20 0.36
MAOA P21397 10/20 0.36
KDM1A O60341 8/20 0.36
HDAC4 P56524 1/20 0.36
CYP2C19 P33261 4/20 0.35
CYP2B6 P20813 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 2/20 0.35
CYP2C9 P11712 2/20 0.35
LMNA P02545 2/20 0.35
TAAR1 Q96RJ0 2/20 0.35
CYP3A4 P08684 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
CYP2A6 P11509 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2C P28335 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16817817 0.84 MEN1 (0.40) MEN1KMT2ACHRNA7MAOBMAOA
SCHEMBL10751693 0.81 MEN1 (0.47) MEN1KMT2ACHRNA7MAOBMAOA
SCHEMBL10736010 0.81 MEN1 (0.47) MEN1KMT2ACHRNA7MAOBMAOA
SCHEMBL418730 0.81 MEN1 (0.47) MEN1KMT2ACHRNA7MAOBMAOA
SCHEMBL10751690 0.81 MEN1 (0.47) MEN1KMT2ACHRNA7MAOBMAOA
SCHEMBL20547603 0.77 MAOB (0.45) MEN1KMT2ACHRNA7MAOBMAOA
SCHEMBL13735039 0.77 MEN1 (0.47) MEN1KMT2ACHRNA7MAOBMAOA
SCHEMBL395631 0.77 MEN1 (0.47) MEN1KMT2ACHRNA7MAOBMAOA
SCHEMBL779571 0.74 CHRNA7 (0.45) MEN1KMT2ACHRNA7MAOBMAOA
SCHEMBL28843512 0.73 CHRNA7 (0.41) MEN1KMT2ACHRNA7MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1146204-A Oxazole heterocyclic aromatic compound and use thereof JAPAN TOBACCO INC (JP) 1997-03-26 CN disclosed