Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4265916 | 0.96 | TSHR (0.48) | TSHRALDH1A1HAO1THRBFNTA | |
| SCHEMBL4278622 | 0.96 | TSHR (0.48) | TSHRALDH1A1HAO1THRBFNTA | |
| SCHEMBL11132679 | 0.96 | TSHR (0.43) | TSHRALDH1A1HAO1THRBFNTA | |
| SCHEMBL4275962 | 0.96 | TSHR (0.48) | TSHRALDH1A1HAO1THRBFNTA | |
| SCHEMBL10753755 | 0.96 | TSHR (0.48) | TSHRALDH1A1HAO1THRBFNTA | |
| SCHEMBL1899577 | 0.96 | TSHR (0.43) | TSHRALDH1A1HAO1THRBFNTA | |
| SCHEMBL4276362 | 0.94 | ALDH1A1 (0.50) | TSHRALDH1A1HAO1THRBFNTA | |
| SCHEMBL432887 | 0.94 | TSHR (0.44) | TSHRALDH1A1HAO1THRBFNTA | |
| SCHEMBL3278392 | 0.93 | TSHR (0.48) | TSHRALDH1A1HAO1THRBFNTA | |
| SCHEMBL3278066 | 0.93 | TSHR (0.48) | TSHRALDH1A1HAO1THRBFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4714532-A | INCORPORATING OLIGOMER OF 1,3-BUTADIENE | AKZO NV (NL) | 1987-12-22 | — | — | US | disclosed |