Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL8605999 | 0.91 | TDP1 (0.41) | CYP3A4MAPTUSP2SMN1; SMN2LMNA | |
| Propylene Glycol SCHEMBL243614 | 0.91 | TDP1 (0.41) | CYP3A4MAPTUSP2SMN1; SMN2LMNA | |
| Glycerin SCHEMBL27795609 | 0.88 | LMNA (0.42) | CYP3A4MAPTUSP2SMN1; SMN2LMNA | |
| Isopropyl Alcohol SCHEMBL28174792 | 0.88 | TDP1 (0.44) | CYP3A4MAPTUSP2SMN1; SMN2LMNA | |
| Propylene Glycol SCHEMBL2910019 | 0.86 | TDP1 (0.43) | CYP3A4MAPTUSP2SMN1; SMN2LMNA | |
| SCHEMBL31217853 | 0.85 | TSHR (0.47) | CYP3A4MAPTUSP2SMN1; SMN2LMNA | |
| SCHEMBL64376 | 0.85 | — | — | |
| Propylene Glycol SCHEMBL28099194 | 0.84 | TDP1 (0.42) | CYP3A4MAPTUSP2SMN1; SMN2LMNA | |
| Propylene Glycol SCHEMBL7626719 | 0.84 | TDP1 (0.42) | CYP3A4MAPTUSP2SMN1; SMN2LMNA | |
| Allyl Alcohol SCHEMBL27764218 | 0.83 | TSHR (0.43) | CYP3A4MAPTUSP2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017039-B2 | Fluorescent body for use in a near-ultraviolet excitation light-emitting element | NIIGATA UNIVERSITY (JP) | 2011-09-13 | — | — | US | disclosed |
| US-7964112-B2 | Phosphor and phosphor paste | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-21 | — | — | US | disclosed |
| EP-1892279-B1 | PHOSPHOR, PHOSPHOR PASTE AND LIGHT-EMITTING DEVICE | SUMITOMO CHEMICAL CO (JP) | 2011-01-26 | — | — | EP | disclosed |
| US-20110012060-A1 | FLUORESCENT BODY FOR USE IN A NEAR-ULTRAVIOLET EXCITATION LIGHT-EMITTING ELEMENT | NIIGATA UNIVERSITY (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20100237287-A1 | PHOSPHOR, PHOSPHOR PASTE CONTAINING THE SAME, AND LIGHT-EMITTING DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-23 | — | — | US | disclosed |
| US-20100224828-A1 | PHOSPHOR, PHOSPHOR PASTE CONTAINING THE SAME, AND LIGHT-EMITTING DEVICE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-09-09 | — | — | US | disclosed |
| US-20100140549-A1 | METAL MIXED OXIDE, PHOSPHOR, PHOSPHOR PASTE AND LIGHT-EMITTING DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-10 | — | — | US | disclosed |
| US-20100102276-A1 | PHOSPHOR FOR ULTRAVIOLET EXCITED LIGHT-EMITTING DEVICE, PHOSPHOR PASTE, AND ULTRAVIOLET EXCITED LIGHT-EMITTING DEVICE | SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20090315448-A1 | PHOSPHOR, PHOSPHOR PASTE AND LIGHT EMITTING DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-12-24 | — | — | US | disclosed |
| US-7528537-B2 | Phosphor, phosphor paste, and vacuum ultraviolet excited light-emitting device | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-05 | — | — | US | disclosed |
| EP-1892279-A1 | PHOSPHOR, PHOSPHOR PASTE AND LIGHT-EMITTING DEVICE | Sumitomo Chemical Company, Limited (JP) | 2008-02-27 | — | — | EP | disclosed |
| US-20070247051-A1 | Phosphor, Phosphor Paste and Light-Emitting Device | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1811009-A1 | PHOSPHOR, PHOSPHOR PASTE AND LIGHT-EMITTING DEVICE | Sumitomo Chemical Company, Limited (JP) | 2007-07-25 | — | — | EP | disclosed |
| US-20070114496-A1 | Phosphor, phosphor paste, and vacuum ultraviolet excited light-emitting device | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-24 | — | — | US | disclosed |
| US-20070018137-A1 | Fluorescent material and fluorescent material paste | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-01-25 | — | — | US | disclosed |
| EP-1705233-A1 | PHOSPHOR, PHOSPHOR PASTE AND LUMINESCENT ELEMENT BEING EXITED BY VACUUM ULTRAVIOLET RAY | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |
| EP-1683849-A1 | FLUORESCENT MATERIAL AND FLUORESCENT MATERIAL PASTE | Sumitomo Chemical Company, Limited (JP) | 2006-07-26 | — | — | EP | disclosed |