Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758423 | 0.93 | GAA (0.51) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL10761180 | 0.87 | GAA (0.59) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL10755969 | 0.87 | ALDH1A1 (0.43) | GAACDK1MAPTTP53KDM4E | |
| SCHEMBL10935429 | 0.86 | GAA (0.58) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL10751460 | 0.85 | GAA (0.57) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL10754029 | 0.85 | GAA (0.57) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL10758532 | 0.84 | GAA (0.46) | GAAMAPTKMT2AALDH1A1TSHR | |
| SCHEMBL9662420 | 0.83 | GAA (0.55) | GAACDK1CYP1A2MAPTTP53 | |
| SCHEMBL10758089 | 0.83 | ALDH1A1 (0.40) | GAACDK1MAPTTP53KMT2A | |
| SCHEMBL10933888 | 0.83 | KMT2A (0.40) | GAAKMT2AKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041404-B1 | HERBICIDAL THIOPHENESULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-30 | — | — | EP | claimed |
| US-4398939-A | Herbicidal thiophenesulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-08-16 | — | — | US | claimed |
| US-4645529-A | POSTEMERGENCE AND PREEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-02-24 | — | — | US | disclosed |
| US-4523943-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-18 | — | — | US | disclosed |
| EP-0041404-B1 | HERBICIDAL THIOPHENESULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-30 | — | — | EP | disclosed |
| US-4398939-A | Herbicidal thiophenesulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0041404-A2 | Herbicidal thiophenesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-12-09 | — | — | EP | disclosed |