SCHEMBL10754167

SCHEMBL10754167

COC(=O)c1sccc1S(=O)(=O)NC(=O)Nc1nc(C)cc(C)n1

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 3/20 0.49
GAA P10253 2/20 0.44
MAPT P10636 3/20 0.43
HTT P42858 1/20 0.43
PPARG P37231 1/20 0.42
PPARD Q03181 1/20 0.42
PPARA Q07869 1/20 0.42
ALOX15 P16050 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10753757 0.92 GAA (0.50) EDNRAGAAMAPTPPARGPPARD
SCHEMBL10752070 0.89 EDNRA (0.50) EDNRAGAAMAPTPPARGPPARD
SCHEMBL10754353 0.88 EDNRA (0.47) EDNRAGAAMAPTALOX15MEN1
SCHEMBL10498166 0.88 EDNRA (0.42) EDNRAGAAMAPTPPARGPPARD
SCHEMBL10752205 0.87 GAA (0.57) EDNRAGAAMAPTPPARGPPARD
SCHEMBL9833690 0.87 EDNRA (0.46) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL9833684 0.87 EDNRA (0.46) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL10754403 0.86 EDNRA (0.47) EDNRAGAAMAPTPPARGPPARD
Sulfometuron Methyl SCHEMBL7635126 0.85 PPARG (0.39) EDNRAGAAMAPTPPARGPPARD
Thifensulfuron-Methyl SCHEMBL20723624 0.84 EDNRA (0.46) EDNRAGAAMAPTPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0030142-B1 HERBICIDAL UREAS, PREPARATION, COMPOSITIONS AND USE THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-12-05 EP claimed
EP-0030142-A2 Herbicidal ureas, preparation, compositions and use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-10 EP claimed
US-4701535-A CHEMICAL INTERMEDIATES FOR HERBICIDES, PLANT GROWTH REGULATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-10-20 US disclosed
US-4599103-A PRE-AND POSTEMERGENCE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-07-08 US disclosed
EP-0030142-B1 HERBICIDAL UREAS, PREPARATION, COMPOSITIONS AND USE THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-12-05 EP disclosed
US-4481029-A HERBICIDES, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-11-06 US disclosed
EP-0030142-A2 Herbicidal ureas, preparation, compositions and use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-10 EP disclosed