Pyridine

Pyridine

SCHEMBL10754259

Fc1nc(F)c(F)c(F)c1F.c1ccncc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
NAPRT Q6XQN6 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NOTUM Q6P988 1/20 0.31
MAPK14 Q16539 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL10951607 0.86 TSHR (0.64) TSHRNAPRTTDP1NOTUMMEN1
Pyridine SCHEMBL10754731 0.78 TSHR (0.41) TSHRNAPRTTDP1MEN1KMT2A
SCHEMBL188694 0.76 MEN1 (0.41) MEN1MAPTHTTKMT2A
Pyridine SCHEMBL4577146 0.75 TSHR (0.56) TSHRNAPRTTDP1NOTUMMAPK14
Pyridine SCHEMBL27885313 0.74 TSHR (0.47) TSHRNAPRTTDP1NOTUM
Pyridine SCHEMBL4950936 0.72 TSHR (0.90) TSHRNAPRTTDP1NOTUMMEN1
Pyridine SCHEMBL11313895 0.72
Pyridine SCHEMBL29404917 0.72
Pyridine SCHEMBL528579 0.72 TSHR (0.90) TSHRNAPRTTDP1NOTUMMEN1
Pyridine SCHEMBL5666855 0.72 TSHR (0.45) TSHRNAPRTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4680406-A Process for fluorinating halogenated organo-compounds THE DOW CHEMICAL COMPANY (US) 1987-07-14 US disclosed