Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10756846 | 0.92 | MAPK1 (0.53) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL10756852 | 0.92 | MAPK1 (0.53) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL10790068 | 0.91 | MAPK1 (0.52) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL10790048 | 0.82 | TDP1 (0.49) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL10790053 | 0.82 | TDP1 (0.49) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL10756805 | 0.82 | TDP1 (0.52) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL10756810 | 0.82 | TDP1 (0.52) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL10791941 | 0.81 | PLCG1 (0.57) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL10791948 | 0.81 | PLCG1 (0.57) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL10794279 | 0.81 | TDP1 (0.52) | ALDH1A1KDM4EMAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4683227-A | CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| EP-0211526-A2 | Cephalosporins, their preparation and formulations | ELI LILLY AND COMPANY (US) | 1987-02-25 | — | — | EP | disclosed |