Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SPOP | O43791 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10791948 | 1.00 | PLCG1 (0.57) | PLCG1ALDH1A1L3MBTL1SPOPTDP1 | |
| SCHEMBL11673833 | 0.82 | PLCG1 (0.65) | PLCG1ALDH1A1L3MBTL1SPOPTDP1 | |
| SCHEMBL11673831 | 0.82 | PLCG1 (0.65) | PLCG1ALDH1A1L3MBTL1SPOPTDP1 | |
| SCHEMBL10755756 | 0.81 | ALDH1A1 (0.48) | ALDH1A1SPOPTDP1MAPK1MAPT | |
| SCHEMBL11512916 | 0.79 | PLCG1 (0.81) | PLCG1ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL8664798 | 0.79 | PLCG1 (0.81) | PLCG1ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL8664795 | 0.79 | PLCG1 (0.81) | PLCG1ALDH1A1L3MBTL1TDP1MAPK1 | |
| SCHEMBL10790176 | 0.79 | PLCG1 (0.66) | PLCG1ALDH1A1L3MBTL1SPOPTDP1 | |
| SCHEMBL10790178 | 0.79 | PLCG1 (0.66) | PLCG1ALDH1A1L3MBTL1SPOPTDP1 | |
| SCHEMBL11330160 | 0.79 | PLCG1 (0.61) | PLCG1ALDH1A1L3MBTL1SPOPTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4683227-A | CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1987-07-28 | — | — | US | disclosed |