Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18134205 | 0.77 | NUDT1 (0.66) | NUDT1POLBCYP1A2CYP2C19NPC1 | |
| SCHEMBL7407822 | 0.76 | NUDT1 (0.49) | NUDT1POLBCYP1A2CYP2C19KDM4E | |
| SCHEMBL12074772 | 0.75 | NUDT1 (0.64) | NUDT1POLBCYP1A2CYP2C19NPC1 | |
| SCHEMBL22930422 | 0.75 | NUDT1 (0.60) | NUDT1POLBCYP1A2CYP2C19NPC1 | |
| SCHEMBL11099815 | 0.74 | NUDT1 (0.62) | NUDT1POLBCYP1A2CYP2C19NPC1 | |
| SCHEMBL11494409 | 0.74 | NUDT1 (0.49) | NUDT1POLBCYP1A2CYP2C19NPC1 | |
| SCHEMBL2844487 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10752783 | 0.72 | NUDT1 (0.60) | NUDT1POLBCYP1A2CYP2C19NPC1 | |
| SCHEMBL18072499 | 0.72 | NUDT1 (1.00) | NUDT1POLBCYP1A2CYP2C19NPC1 | |
| SCHEMBL11464975 | 0.72 | NUDT1 (0.67) | NUDT1POLBCYP1A2CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4684395-A | PLANT GROWTH REGULATORS, HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-08-04 | — | — | US | disclosed |
| EP-0009419-B1 | AGRICULTURAL SULFONAMIDES, AND PREPARATION AND USE THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-01-02 | — | — | EP | disclosed |
| US-4501607-A | Herbicidal triazine sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
| US-4214890-A | PRE- AND POST-EMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-07-29 | — | — | US | disclosed |