SCHEMBL10757172

SCHEMBL10757172

O=C1NC(=O)C(c2ccc(F)s2)O1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10758462 0.79 CA2 (0.47) CA2
SCHEMBL10756658 0.79 CA2 (0.47) CA2
SCHEMBL10762082 0.74 CA2 (0.54) CA2
SCHEMBL10758008 0.71 CA2 (0.42) CA2
SCHEMBL10756735 0.70 CA2 (0.53) CA2
SCHEMBL10758397 0.70 CA2 (0.53) CA2
SCHEMBL11040315 0.69 CA2 (0.67) CA2
SCHEMBL11039035 0.68 CA2 (0.55) CA2
SCHEMBL10758799 0.68 CA2 (0.50) CA2
SCHEMBL10763085 0.68 CA2 (0.46) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4695634-A Hypoglycemic 5-substituted oxazolidine-2,4-diones PFIZER INC. (US) 1987-09-22 US disclosed
US-4622406-A CHEMICAL INTERMEDIATES, TRIMETHYLSILOXY COMPOUNDS PFIZER INC. (US) 1986-11-11 US disclosed
US-4562267-A Intermediates of hypoglycemic 5-substituted oxazolidine-2,4-diones PFIZER INC. (US) 1985-12-31 US disclosed
US-4423233-A ALPHA-HYDROXY CARBOXIMIDATE INTERMEDIATES PFIZER INC. (US) 1983-12-27 US disclosed
US-4381308-A Hypoglycemic 5-substituted oxazolidine-2,4-diones PFIZER INC. (US) 1983-04-26 US disclosed
US-4332952-A Hypoglycemic 5-substituted oxazolidine-2,4-diones PFIZER INC. (US) 1982-06-01 US disclosed