SCHEMBL10757233

SCHEMBL10757233

O=C(Nc1c[nH]nn1)c1ccccc1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.51
KMT2A Q03164 8/20 0.51
NPC1 O15118 8/20 0.51
KDM4E B2RXH2 7/20 0.51
LMNA P02545 6/20 0.51
HTT P42858 6/20 0.51
TP53 P04637 5/20 0.51
HPGD P15428 4/20 0.51
HSD17B10 Q99714 4/20 0.51
GAA P10253 3/20 0.51
POLB P06746 2/20 0.49
ALPL P05186 1/20 0.49
SMN1; SMN2 Q16637 3/20 0.47
MPO P05164 1/20 0.47
HIF1A Q16665 1/20 0.47
RAB9A P51151 7/20 0.47
PNLIP P16233 2/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPK1 P28482 1/20 0.46
NFKB1 P19838 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11128707 0.79 MEN1 (0.56) MEN1KMT2ANPC1TP53RAB9A
SCHEMBL11706669 0.76 CDC25B (0.44) MEN1KMT2ANPC1HTTPOLB
SCHEMBL29493451 0.76 KDM4E (0.53) MEN1KMT2ANPC1KDM4ELMNA
SCHEMBL3421840 0.76 KDM4E (0.53) MEN1KMT2ANPC1KDM4ELMNA
SCHEMBL11555561 0.76 KMT2A (0.45) KMT2ANPC1TP53POLBSMN1; SMN2
SCHEMBL17675194 0.76 MEN1 (0.71) MEN1KMT2ANPC1KDM4ELMNA
SCHEMBL27264992 0.72 GSTA1 (0.45) NPC1KDM4ELMNAHTTHPGD
SCHEMBL11105640 0.72 KDM4E (0.60) MEN1KMT2ANPC1KDM4ELMNA
SCHEMBL79490 0.72 KDM4E (0.52) MEN1KMT2ANPC1KDM4ELMNA
SCHEMBL10912483 0.71 NPC1 (0.58) MEN1KMT2ANPC1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4433542-A1 SILICONE RUBBER COMPOSITION Dow Silicones Corporation (US) 2024-09-25 EP claimed
WO-2023087233-A1 SILICONE RUBBER COMPOSITION DOW SILICONES CORPORATION (US) 2023-05-25 WO claimed
EP-0054420-B1 FUNCTIONAL ELECTRIC DEVICES MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1987-03-11 EP claimed
US-4426546-A FUNCTIONAL LAYER AND PAIR OF COPPER, OR COPPER ALLOY, ELECTRODES MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1984-01-17 US claimed
EP-0054420-A2 Functional electric devices MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-06-23 EP claimed
US-20250109256-A1 SILICONE RUBBER COMPOSITION DOW SILICONES CORP (US) 2025-04-03 US disclosed
EP-4433542-A1 SILICONE RUBBER COMPOSITION Dow Silicones Corporation (US) 2024-09-25 EP disclosed
EP-4433542-A1 SILICONE RUBBER COMPOSITION Dow Silicones Corporation (US) 2024-09-25 EP disclosed
WO-2023087233-A1 SILICONE RUBBER COMPOSITION DOW SILICONES CORPORATION (US) 2023-05-25 WO disclosed
WO-2023087233-A1 SILICONE RUBBER COMPOSITION DOW SILICONES CORPORATION (US) 2023-05-25 WO disclosed
EP-0054420-B1 FUNCTIONAL ELECTRIC DEVICES MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1987-03-11 EP disclosed
US-4426546-A FUNCTIONAL LAYER AND PAIR OF COPPER, OR COPPER ALLOY, ELECTRODES MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1984-01-17 US disclosed
EP-0054420-A2 Functional electric devices MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-06-23 EP disclosed