GSTA1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL3713736	0.80	9/20
SCHEMBL314096	0.78	9/20
Ethacrynic Acid (SCHEMBL42210)	0.76	9/20
SCHEMBL313019	0.67	9/20
SCHEMBL1525419	0.65	9/20
SCHEMBL1523469	0.64	9/20
SCHEMBL4411487	0.64	9/20
SCHEMBL313295	0.63	9/20
Ethacrynic Acid (SCHEMBL6906762)	0.63	9/20
SCHEMBL1524793	0.63	9/20
SCHEMBL4407253	0.63	9/20
SCHEMBL4408419	0.60	9/20
SCHEMBL4415347	0.60	9/20
SCHEMBL312767	0.60	9/20
SCHEMBL6210580	0.58	9/20
SCHEMBL4208074	0.58	9/20
Glutathione (SCHEMBL3765549)	0.57	9/20
SCHEMBL1523930	0.55	9/20
SCHEMBL1524497	0.54	9/20
SCHEMBL1524705	0.54	9/20

Clinical trials — most relevant to GSTA1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma	PHASE3	COMPLETED
Cysteine Supplementation in Critically Ill Neonates	PHASE2/PHASE3	UNKNOWN
Paracetamol Toxicity in Septic Patients	PHASE3	SUSPENDED
Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled O3 Exposure	PHASE2	COMPLETED
Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled LPS	PHASE1/PHASE2	COMPLETED
Effect of Acetaminophen and N-Acetylcysteine on Liver Metabolism on Homocystinuria	PHASE1/PHASE2	SUSPENDED
Neoadjuvant Chemoradiotherapy Followed By Surgery in Treating Patients With Limited-Stage Small Cell Lung Cancer	PHASE1	COMPLETED
Celecoxib in Preventing Colorectal Cancer in Young Patients With a Genetic Predisposition for Familial Adenomatous Polyposis	PHASE1	COMPLETED
Na-GST-1/Alhydrogel With or Without CpG 10104 in Gabonese Adults	PHASE1	COMPLETED
A Dose Escalation Trial of Radiation Therapy (RT) for Hepatocellular Carcinoma (HCC)	PHASE1	UNKNOWN
Tolerability of Enteral NAC in Infants	PHASE1	NOT_YET_RECRUITING
Pharmacokinetics and Safety of GST-HG171 Tablets in Subjects With Impaired and Normal Liver Function	PHASE1	COMPLETED
Pharmacokinetics, Metabolism and Analgesic Effects of Flupirtine	PHASE1	COMPLETED
The Conversion of ENcapsulated GlucorAphanin, Gut Microbiota Phylogeny and gEnotype Study (ENGAGE)	nan	COMPLETED
Broccoli and Vascular Health Study	nan	COMPLETED
Studying Urine and Blood Samples in Women With Newly Diagnosed Breast Cancer	nan	COMPLETED
Dietary and Genetic Factors in Asthma & Chronic Bronchitis in a Cohort of Chinese Singaporeans	nan	COMPLETED
S8516-S8736-S9125-S9240 Research Study of Genes in Tissue Samples From Patients With B-cell Non-Hodgkin Lymphoma	nan	COMPLETED
Mechanisms of Response to Diesel Exhaust in Subjects With Asthma	nan	WITHDRAWN
DNA Analysis of Blood and Tissue from Patients with Lung Cancer	nan	RECRUITING
Cancer and Hearing Loss Related in Children	nan	COMPLETED
Factors in Childhood Lung Susceptibility to Pollution	nan	COMPLETED
Molecular Epidemiology of Childhood Leukemia (Aka The California Childhood Leukemia Study)	nan	COMPLETED
Polymorphisms and Busulfan Pharmacokinetic Study	nan	UNKNOWN
Effects of Green Tea Extract (GTE) on Systemic Oxidative and Antioxidative Status in Chinese Patients With Stable Asthma	nan	COMPLETED
Genetic Polymorphisms in UGT1A6 and UGT2B7 in Asian Population: Association With Lung Cancer Phenotype	nan	UNKNOWN
Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS	nan	RECRUITING
Gene-by-Smoking Interactions and Risk of Atherosclerosis - Ancillary to ARIC	nan	COMPLETED
Epigenetic Effect Modifications With Ozone Exposure on Healthy Volunteers	nan	COMPLETED
Genetic and Environmental Risk Factors Related to Esophageal Cancer	nan	ACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a GSTA1 binder may also engage these)

Protein	Name	Similarity
Q16772	—	1.000	Q16772 →
GSTA2	Glutathione S-transferase A2	1.000	landscape →
Q08863	—	1.000	Q08863 →
Q08393	—	1.000	Q08393 →
Q7RTV2	—	1.000	Q7RTV2 →
Q08392	—	1.000	Q08392 →
Q28035	—	1.000	Q28035 →
P46418	—	1.000	P46418 →
P00502	—	1.000	P00502 →
P04903	—	1.000	P04903 →
P04904	—	1.000	P04904 →
P13745	—	1.000	P13745 →
P80894	—	1.000	P80894 →
P81706	—	1.000	P81706 →
Q08862	—	1.000	Q08862 →
O18879	—	1.000	O18879 →
P14942	—	1.000	P14942 →
P24472	—	1.000	P24472 →
Q54QV7	—	0.999	Q54QV7 →
P26697	—	0.999	P26697 →
P30114	—	0.998	P30114 →
P30115	—	0.998	P30115 →
P46434	—	0.998	P46434 →
Q6AXY0	—	0.998	Q6AXY0 →
P91252	—	0.997	P91252 →
O15217	—	0.997	O15217 →
P51781	—	0.997	P51781 →
P09792	—	0.996	P09792 →
P26624	—	0.996	P26624 →
Q9ZW26	—	0.996	Q9ZW26 →