SCHEMBL10757286

SCHEMBL10757286

NC(c1ccccc1)(c1ccccc1)c1c[nH]c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 2/20 0.46
ATM Q13315 2/20 0.42
GPR84 Q9NQS5 3/20 0.41
MEN1 O00255 2/20 0.41
CYP3A4 P08684 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.41
AHR P35869 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP2A6 P11509 2/20 0.41
HTR2A P28223 2/20 0.41
HTR2C P28335 2/20 0.41
MPO P05164 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
NFKB1 P19838 1/20 0.41
HTR1D P28221 1/20 0.41
HTR1B P28222 1/20 0.41
HTR7 P34969 1/20 0.41
CTSK P43235 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14694211 0.82 ATM (0.50) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL7915295 0.81 ATM (0.45) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL28686221 0.78 ATM (0.47) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL28695856 0.77 HTR2A (0.45) ATMGPR84MEN1CYP3A4KMT2A
Hydrochloric Acid SCHEMBL8129884 0.77 CYP2A6 (0.44) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL7192679 0.77 ATM (0.50) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL17232880 0.77 ATM (0.50) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL28864004 0.76 ATM (0.52) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL27609985 0.74 ATM (0.44) ATMGPR84MEN1CYP3A4KMT2A
SCHEMBL7022975 0.74 ATM (0.50) ATMGPR84MEN1CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4697018-A CARBONLESS DUPLICATION OR THERMAL MARKING DYES THE HILTON-DAVIS CHEMICAL CO. (US) 1987-09-29 US disclosed
US-4558137-A CHROMAGENS, PRESSURE AND HEAT SENSITIVE CARBONLESS DUPLICATING SYSTEMS THE HILTON-DAVIS CHEMICAL CO. (US) 1985-12-10 US disclosed
US-4403791-A Carbonless duplicating and marking systems STERLING DRUG INC. (US) 1983-09-13 US disclosed