Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915295 | 0.87 | ATM (0.45) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL7022975 | 0.84 | ATM (0.50) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL14694211 | 0.84 | ATM (0.50) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL5596105 | 0.82 | ATM (0.48) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL2789076 | 0.82 | CTNNB1 (0.51) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL1685393 | 0.82 | ATM (0.54) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL13335152 | 0.82 | ATM (0.54) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL799601 | 0.82 | ATM (0.54) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL29885789 | 0.82 | ATM (0.54) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL30437029 | 0.82 | ATM (0.54) | ATMGPR84MEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232052-A | Tetraindolylmethane compound and preparation method and application thereof | 南京工业大学 | 2022-10-25 | — | — | CN | claimed |
| CN-115232052-A | Tetraindolylmethane compound and preparation method and application thereof | 南京工业大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232052-A | Tetraindolylmethane compound and preparation method and application thereof | 南京工业大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-115232052-A | Tetraindolylmethane compound and preparation method and application thereof | 南京工业大学 | 2022-10-25 | — | — | CN | disclosed |