Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | MGLL | Q99685 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3806103 | 0.76 | GBA1 (0.46) | GBA1GAATP53MMP1MMP3 | |
| SCHEMBL9017626 | 0.74 | GBA1 (0.49) | GBA1GAATP53MMP1MMP3 | |
| SCHEMBL9017602 | 0.74 | GBA1 (0.49) | GBA1GAATP53MMP1MMP3 | |
| SCHEMBL7192019 | 0.70 | GAA (0.50) | GBA1GAATP53MMP1MMP3 | |
| SCHEMBL7194468 | 0.66 | GAA (0.41) | GBA1GAATP53MMP1MMP3 | |
| SCHEMBL35106 | 0.64 | MEN1 (0.30) | — | |
| SCHEMBL11403361 | 0.62 | GBA1 (0.56) | GBA1GAATP53PTGS1PTGS2 | |
| Hexane SCHEMBL9392301 | 0.62 | TSHR (0.50) | — | |
| SCHEMBL10382407 | 0.61 | GBA1 (0.55) | GBA1GAATP53PTGS1PTGS2 | |
| SCHEMBL11359259 | 0.61 | GBA1 (0.70) | GBA1GAATP53PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448485-A2 | ANALYTE SENSOR | Dexcom, Inc. (US) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011003035-A2 | ANALYTE SENSOR | DEXCOM, INC. (US) | 2011-01-06 | — | — | WO | disclosed |