Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 4/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017602 | 1.00 | GBA1 (0.49) | GBA1PTGS1PTGS2MGLLFAAH | |
| SCHEMBL3806103 | 0.98 | GBA1 (0.46) | GBA1PTGS1PTGS2MGLLFAAH | |
| SCHEMBL7192019 | 0.92 | GAA (0.50) | GBA1PTGS1TP53GAAMMP1 | |
| SCHEMBL7194468 | 0.88 | GAA (0.41) | GBA1PTGS1PTGS2MGLLFAAH | |
| SCHEMBL819149 | 0.81 | ELANE (0.38) | GBA1PTGS1TP53GAAMMP1 | |
| SCHEMBL1358142 | 0.78 | L3MBTL1 (0.41) | GBA1PTGS1TP53GAAMMP1 | |
| SCHEMBL7887401 | 0.77 | PTGS1 (0.42) | GBA1PTGS1PTGS2MGLLFAAH | |
| SCHEMBL818514 | 0.76 | — | — | |
| SCHEMBL1075742 | 0.74 | GBA1 (0.40) | GBA1PTGS1PTGS2MGLLFAAH | |
| SCHEMBL7203140 | 0.73 | CYP3A4 (0.34) | TP53GAAMMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311632-B1 | SURFACE ACTIVE LACTAMS | ISP INVESTMENTS INC (US) | 1996-05-29 | — | — | EP | disclosed |
| EP-0311632-A4 | SURFACE ACTIVE LACTAMS | — | 1990-12-27 | — | — | EP | disclosed |
| EP-0311632-A1 | SURFACE ACTIVE LACTAMS. | GAF CORP (US) | 1989-04-19 | — | — | EP | disclosed |
| WO-1988000184-A1 | SURFACE ACTIVE LACTAMS | GAF CORPORATION (US) | 1988-01-14 | — | — | WO | disclosed |