Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 3/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539335 | 0.90 | L3MBTL1 (0.57) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9539332 | 0.90 | L3MBTL1 (0.57) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27584197 | 0.89 | L3MBTL1 (0.65) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7571102 | 0.86 | L3MBTL1 (0.53) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6312460 | 0.85 | L3MBTL1 (0.57) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6308152 | 0.85 | L3MBTL1 (0.57) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6308156 | 0.85 | L3MBTL1 (0.57) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9383025 | 0.85 | L3MBTL1 (0.59) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9383029 | 0.85 | L3MBTL1 (0.59) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28410876 | 0.85 | L3MBTL1 (0.59) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4684653-A | ANTITUMOR AGENTS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1987-08-04 | — | — | US | disclosed |