Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27173944 | 0.85 | SIGMAR1 (0.67) | SIGMAR1SLC6A4 | |
| SCHEMBL13060794 | 0.81 | TAAR1 (0.52) | SIGMAR1SLC6A4HTR2AHRH1 | |
| SCHEMBL1618760 | 0.81 | TAAR1 (0.52) | SIGMAR1SLC6A4HTR2AHRH1 | |
| SCHEMBL1618758 | 0.81 | TAAR1 (0.52) | SIGMAR1SLC6A4HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL6738145 | 0.81 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL22558398 | 0.81 | SLC6A4 (0.62) | SIGMAR1SLC6A4 | |
| SCHEMBL13061020 | 0.80 | SIGMAR1 (0.41) | SIGMAR1SLC6A4HTR2AHRH1 | |
| SCHEMBL23137160 | 0.79 | HTR2A (0.42) | SIGMAR1SLC6A4HTR2AHRH1 | |
| SCHEMBL13006637 | 0.79 | SIGMAR1 (0.47) | SIGMAR1SLC6A4HTR2AHRH1 | |
| SCHEMBL13006613 | 0.79 | SIGMAR1 (0.47) | SIGMAR1SLC6A4HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122018-B1 | IMPROVEMENTS IN AND RELATING TO PHARMACOLOGICALLY ACTIVE TRIPEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |
| US-4510082-A | NONHABIT-FORMING ANALGESICS | ELI LILLY AND COMPANY (US) | 1985-04-09 | — | — | US | disclosed |
| EP-0122018-A2 | Improvements in and relating to pharmacologically active tripeptide derivatives | ELI LILLY AND COMPANY (US) | 1984-10-17 | — | — | EP | disclosed |
| US-4473497-A | Pharmacologically active peptides | ELI LILLY AND COMPANY (US) | 1984-09-25 | — | — | US | disclosed |