Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10759256 | 1.00 | TMEM97 (0.41) | TMEM97SIGMAR1FFAR1CYP26A1CYP26B1 | |
| SCHEMBL10758227 | 0.88 | EPHX2 (0.41) | TMEM97SIGMAR1SMN1; SMN2GAANAMPT | |
| SCHEMBL10753422 | 0.88 | SMN1; SMN2 (0.45) | TMEM97SIGMAR1FFAR1CYP26A1CYP26B1 | |
| SCHEMBL10760974 | 0.88 | SMN1; SMN2 (0.45) | TMEM97SIGMAR1FFAR1CYP26A1CYP26B1 | |
| SCHEMBL10753411 | 0.88 | SMN1; SMN2 (0.45) | TMEM97SIGMAR1FFAR1CYP26A1CYP26B1 | |
| SCHEMBL10754804 | 0.82 | TMEM97 (0.36) | TMEM97SIGMAR1NAMPT | |
| SCHEMBL10757112 | 0.82 | TMEM97 (0.36) | TMEM97SIGMAR1NAMPT | |
| SCHEMBL10760034 | 0.82 | TMEM97 (0.38) | TMEM97SIGMAR1NAMPT | |
| SCHEMBL10758522 | 0.81 | EPHX2 (0.40) | TMEM97SIGMAR1SMN1; SMN2GAANAMPT | |
| SCHEMBL10758933 | 0.78 | TMEM97 (0.41) | TMEM97SIGMAR1CYP26A1CYP26B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4672071-A | Antihypertensive dihydropyridine compositions, optical isomers and intermediates | SYNTEX (U.S.A.) INC. (US) | 1987-06-09 | — | — | US | disclosed |