Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 8/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21869824 | 0.85 | FKBP1A (0.53) | FKBP1AHDAC1HDAC6 | |
| SCHEMBL28663248 | 0.85 | FKBP1A (0.53) | FKBP1AHDAC1HDAC6 | |
| SCHEMBL13385271 | 0.82 | FKBP1A (0.50) | ALDH1A1FKBP1AHPGD | |
| SCHEMBL14299314 | 0.82 | FKBP1A (0.50) | ALDH1A1FKBP1AHPGD | |
| SCHEMBL28669317 | 0.81 | HDAC1 (0.53) | FKBP1AHDAC1HDAC6 | |
| SCHEMBL21869748 | 0.81 | HDAC1 (0.53) | FKBP1AHDAC1HDAC6 | |
| SCHEMBL21869826 | 0.81 | HDAC1 (0.53) | FKBP1AHDAC1HDAC6 | |
| SCHEMBL21869798 | 0.81 | KMT2A (0.62) | ALDH1A1FKBP1AHDAC1HDAC6CYP2C9 | |
| SCHEMBL21869747 | 0.81 | KMT2A (0.62) | ALDH1A1FKBP1AHDAC1HDAC6CYP2C9 | |
| SCHEMBL28663232 | 0.81 | KMT2A (0.62) | ALDH1A1FKBP1AHDAC1HDAC6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661512-A | Adamantanamine derivatives, processes for their preparation and drugs in which they are present | S. A. PANMEDICA (FR) | 1987-04-28 | — | — | US | disclosed |