FKBP1A — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Biricodar (SCHEMBL154547)	1.00	20/20
Biricodar (SCHEMBL355913)	0.85	20/20
SCHEMBL619873	1.00	19/20
SCHEMBL619874	1.00	19/20
SCHEMBL611145	0.80	19/20
SCHEMBL499268	0.80	19/20
SCHEMBL419423	0.79	19/20
SCHEMBL419424	0.79	19/20
SCHEMBL609093	0.77	19/20
Tacrolimus Anhydrous (SCHEMBL298133)	0.76	19/20
SCHEMBL611176	0.68	19/20
SCHEMBL610969	0.64	19/20
SCHEMBL610971	0.64	19/20
SCHEMBL173063	0.63	19/20
SCHEMBL418764	0.57	19/20
SCHEMBL418765	0.57	19/20
SCHEMBL416985	0.56	19/20
SCHEMBL416986	0.56	19/20
SCHEMBL418445	0.55	19/20
SCHEMBL418446	0.55	19/20

Clinical trials — most relevant to FKBP1A by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Topical Metformin Emulgel VS Salicylic Acid Peeling in Treatment of Acne Vulgaris	PHASE4	UNKNOWN
A Study to Evaluate the Efficacy and Safety of Three Fixed Doses of Extended-release Paliperidone in Subjects With Bipolar I Disorder	PHASE3	COMPLETED
A Study to Evaluate the Efficacy and Safety of Flexible Doses of Extended-release (ER) Paliperidone Compared With Flexible Doses of Quetiapine and Placebo in Patients With Bipolar I Disorder	PHASE3	COMPLETED
Monoamine Transporters Genotypes: Risk of PTSD and Related Comorbidities	PHASE3	COMPLETED
Rapamycin for Immunosuppression and B Cell Modulation Post Stem Cell Transplant for Acute Lymphoblastic Leukemia (ALL)	PHASE2	COMPLETED
Neurosteroids for PTSD in Veterans	PHASE2	COMPLETED
Temsirolimus With or Without Megestrol Acetate and Tamoxifen Citrate in Treating Patients With Advanced, Persistent, or Recurrent Endometrial Cancer	PHASE2	COMPLETED
A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors	PHASE1	WITHDRAWN
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors	PHASE1	COMPLETED
In Vivo Lithium Treatment Effects on Gene Expression Levels in Lymphoblastoid Cell Lines From Human Healthy Subjects	PHASE1	COMPLETED
FKBP5 Methylation and Childhood Emotional Abuse in Complex Posttraumatic Stress Disorder: Investigating the Relationship and Its Predictive Role in Therapy Outcome	nan	COMPLETED
Clinical Implications of FKBP5 in Stroke	nan	UNKNOWN
Cortisol, Hippocampus, and Insula in Anorexia Nervosa.	nan	RECRUITING
Quantification of GADD34 Expression in RA	nan	COMPLETED
Torisel in Addition to Standard Chemotherapy With Radiation for Advanced Head and Neck Cancer	nan	WITHDRAWN
A Study on Psychopathological Progress of Early Schizophrenia-Like Disorder (SOPRES)	nan	UNKNOWN
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
Post-Deployment Afghanistan/Iraq Trauma Related Inventory of Traits (PATRIOT): Phase 1 (Feasibility Study)	nan	COMPLETED
Gene Polymorphisms in Tacrolimus Drug Interactions	nan	COMPLETED
Poor Sleep During Pregnancy as Risk Factor for Post-partum Stress and Mental Health	nan	RECRUITING
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)	nan	RECRUITING
Sensorimotor Gating in Schizophrenia	nan	COMPLETED
Establishment of Human Cellular Disease Models for Wilson Disease	nan	COMPLETED
Genetic Predictors of Lithium Response in Bipolar Disorder	nan	COMPLETED
Cerebellar Mutism Syndrome Study	nan	RECRUITING
Identifying New Therapeutic Targets for Lupus Treatment	nan	COMPLETED
Expression of Fas Protein in Skin Biopsies of Participants With Scarring Alopecia	nan	COMPLETED
Major Depression and Messenger RNAs	nan	COMPLETED
Tacrolimus Pharmacokinetic Subpopulations	nan	RECRUITING
Gene First Approach to Connective Tissue Disease	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a FKBP1A binder may also engage these)

Protein	Name	Similarity
P62943	—	1.000	P62943 →
Q62658	—	1.000	Q62658 →
P18203	—	1.000	P18203 →
FKBP1B	Peptidyl-prolyl cis-trans isomerase FKBP1B	1.000	landscape →
Q5VVH2	—	1.000	Q5VVH2 →
O42123	—	1.000	O42123 →
P97534	—	1.000	P97534 →
Q9Z2I2	—	0.999	Q9Z2I2 →
P26883	—	0.998	P26883 →
P48375	—	0.998	P48375 →
P68107	—	0.996	P68107 →
Q8HYX6	—	0.996	Q8HYX6 →
Q6KBA8	—	0.996	Q6KBA8 →
O42993	—	0.994	O42993 →
Q6CF41	—	0.990	Q6CF41 →
Q6BX45	—	0.990	Q6BX45 →
Q754K8	—	0.989	Q754K8 →
O94746	—	0.988	O94746 →
Q6CX30	—	0.988	Q6CX30 →
P20080	—	0.986	P20080 →
P20081	—	0.986	P20081 →
P0CP95	—	0.986	P0CP95 →
Q6M981	—	0.985	Q6M981 →
P0CP94	—	0.985	P0CP94 →
Q4WLV6	—	0.984	Q4WLV6 →
P0A0W2	—	0.984	P0A0W2 →
P0C1J3	—	0.984	P0C1J3 →
Q8LGG0	—	0.983	Q8LGG0 →
Q6FMA3	—	0.983	Q6FMA3 →
Q4W9R2	—	0.982	Q4W9R2 →