SCHEMBL10759793

SCHEMBL10759793

Cc1ccc2nc(C)[c]cc2c1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.50
NCK1 P16333 1/20 0.47
BACE1 P56817 1/20 0.47
ALDH1A1 P00352 2/20 0.42
CYP2A6 P11509 3/20 0.42
NQO2 P16083 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PSMB5 P28074 1/20 0.41
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
PDE3B Q13370 2/20 0.39
PDE3A Q14432 2/20 0.39
TDP1 Q9NUW8 2/20 0.37
PDE2A O00408 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
RAB9A P51151 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1091674 0.85 CYP1A2 (0.54) CYP1A2NCK1BACE1ALDH1A1CYP2A6
SCHEMBL3742742 0.80 CYP1A2 (0.47) CYP1A2NCK1BACE1ALDH1A1CYP2A6
SCHEMBL698703 0.80 ALDH1A1 (0.42) ALDH1A1CYP2A6MEN1KMT2AKDM4E
SCHEMBL2989781 0.80 CYP1A2 (0.47) CYP1A2NCK1BACE1ALDH1A1CYP2A6
SCHEMBL19359 0.78 CYP1A2 (0.46) CYP1A2BACE1ALDH1A1CYP2A6NQO2
SCHEMBL27931348 0.77 CYP1A2 (0.44) CYP1A2NCK1BACE1ALDH1A1CYP2A6
SCHEMBL2251224 0.76 CYP1A2 (0.43) CYP1A2NCK1BACE1ALDH1A1CYP2A6
SCHEMBL2371400 0.72 CYP1A2 (0.62) CYP1A2NCK1BACE1ALDH1A1CYP2A6
SCHEMBL5949423 0.72 AR (0.36) CYP1A2BACE1ALDH1A1CYP2A6MEN1
SCHEMBL693087 0.72 ALDH1A1 (0.42) CYP1A2ALDH1A1CYP2A6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4668275-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-05-26 US disclosed