Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DNA2 | P51530 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718398 | 0.87 | KDM4E (0.43) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL5194351 | 0.87 | CSNK2A2 (0.50) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL10768287 | 0.87 | CSNK2A2 (0.44) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL3812191 | 0.86 | CSNK2A2 (0.49) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL1878010 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL11020660 | 0.82 | KDM4E (0.42) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL13484134 | 0.82 | CSNK2A1 (0.56) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL30307775 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL10914618 | 0.80 | TOP2A (0.47) | KDM4EALDH1A1HPGDCSNK2A2CSNK2B | |
| SCHEMBL5043939 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HPGDCYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215650-A2 | Substituted bridged-diazabicycloalkyl quinolone carboxylic acids | PFIZER INC. (US) | 1987-03-25 | — | — | EP | disclosed |
| EP-0153163-A2 | 7-Substituted-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids; 7-substituted-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acids; their derivatives; and a process for preparing the compounds | WARNER-LAMBERT COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| EP-0106489-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |