Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 5/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10610892 | 0.87 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL6898305 | 0.83 | CYP1A2 (0.39) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11116041 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10755284 | 0.82 | KCNH2 (0.42) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11106635 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11020660 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10753255 | 0.81 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL3239412 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10757080 | 0.81 | KCNH2 (0.45) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11023386 | 0.80 | KCNH2 (0.43) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083032-A2 | Rectally administrable suppository comprising a drug and an adjuvant | MERCK & CO. INC. (US) | 1983-07-06 | — | — | EP | claimed |
| EP-2515907-A1 | FLUOROQUINOLONES FOR THE TREATMENT AND/OR PROPHYLAXIS OF INFLAMMATORY DISEASES | Deutsches Krebsforschungszentrum (DE) | 2012-10-31 | — | — | EP | disclosed |
| EP-1663239-A4 | POTASSIUM CHANNEL MEDIATED DELIVERY OF AGENTS THROUGH THE BLOOD-BRAIN BARRIER | CEDARS SINAI MEDICAL CENTER (US) | 2008-07-23 | — | — | EP | disclosed |
| EP-1827408-A1 | METHOD FOR TREATING SKIN DISORDERS WITH XANTHOPHYLLS | Nu-Tein Co., Inc. (US) | 2007-09-05 | — | — | EP | disclosed |
| EP-1827400-A2 | TOPICAL SKIN PATCH CONTAINING XANTHOPHYLLS | Nu-Tein Co., Inc. (US) | 2007-09-05 | — | — | EP | disclosed |
| EP-1814540-A2 | COMPOSITIONS USEFUL TO TREAT OCULAR NEOVASCULAR DISEASES AND MACULAR DEGENERATION | Nu-Tein Co., Inc. (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006062740-A2 | TOPICAL SKIN PATCH CONTAINING XANTHOPHYLLS | NU-TEIN CO., INC. (US) | 2006-06-15 | — | — | WO | disclosed |
| WO-2006060475-A1 | METHOD FOR TREATING SKIN DISORDERS WITH XANTHOPHYLLS | NU-TEIN CO., INC. (US) | 2006-06-08 | — | — | WO | disclosed |
| EP-1663239-A2 | POTASSIUM CHANNEL MEDIATED DELIVERY OF AGENTS THROUGH THE BLOOD-BRAIN BARRIER | CEDARS-SINAI MEDICAL CENTER (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2006055526-A2 | COMPOSITIONS USEFUL TO TREAT OCULAR NEOVASCULAR DISEASES AND MACULAR DEGENERATION | NU-TEIN CO., INC. (US) | 2006-05-26 | — | — | WO | disclosed |
| WO-2002045695-A2 | HYDROSTATIC DELIVERY SYSTEM FOR CONTROLLED DELIVERY OF AGENT | MACGREGOR ALEXANDER (CA) | 2002-06-13 | — | — | WO | disclosed |
| WO-2002012199-A1 | HETEROCYCLIC MUTILIN ESTERS AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-14 | — | — | WO | disclosed |
| WO-2001092288-A2 | COBALAMIN COMPOUNDS USEFUL AS ANTIBIOTIC AGENTS AND AS IMAGING AGENTS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2001-12-06 | — | — | WO | disclosed |
| EP-0790992-A1 | A NEW PHYSICALLY STABLE SOLID FORM OF A FLUOROQUINOLONE | PHARMACIA & UPJOHN COMPANY (US) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996016055-A1 | A NEW PHYSICALLY STABLE SOLID FORM OF A FLUOROQUINOLONE | PHARMACIA & UPJOHN COMPANY (US) | 1996-05-30 | — | — | WO | disclosed |
| EP-0241206-A2 | Quinoline-3-carboxylic acid derivatives, their preparation and use | Sankyo Company Limited (JP) | 1987-10-14 | — | — | EP | disclosed |
| EP-0203795-A2 | Benzo [i,j] quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same | TOKYO TANABE COMPANY LIMITED (JP) | 1986-12-03 | — | — | EP | disclosed |
| EP-0155006-A2 | Compounds having antibacterial activity, process for their preparation and pharmaceutical compositions containing them | FARMADES S.p.A. (IT) | 1985-09-18 | — | — | EP | disclosed |
| EP-0084011-A1 | Quinoline carboxylic acid complexes with guanidinium carbonate and guanidine | MERCK & CO. INC. (US) | 1983-07-20 | — | — | EP | disclosed |
| EP-0049593-A1 | 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid and metal salts thereof useful in burn therapy | Fox, Charles l., Jr. (US) | 1982-04-14 | — | — | EP | disclosed |