Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622206 | 0.76 | TSHR (0.49) | TSHRBCHELMNAFNTAFNTB | |
| SCHEMBL10622211 | 0.76 | TSHR (0.49) | TSHRBCHELMNAFNTAFNTB | |
| SCHEMBL971738 | 0.76 | BCHE (0.44) | BCHENMT2NMT1SIGMAR1EPHX1 | |
| SCHEMBL7645602 | 0.76 | EPHX1 (0.40) | TSHRFNTAFNTBPGGT1BEPHX1 | |
| SCHEMBL11497983 | 0.76 | EPHX1 (0.40) | TSHRFNTAFNTBPGGT1BEPHX1 | |
| SCHEMBL9191480 | 0.75 | RNPEP (0.39) | TSHRLMNAFNTAFNTBPGGT1B | |
| SCHEMBL9190837 | 0.75 | TSHR (0.38) | TSHRLMNAFNTAFNTBPGGT1B | |
| SCHEMBL13360907 | 0.72 | CA12 (0.38) | TSHRLMNAFNTAFNTBPGGT1B | |
| SCHEMBL12247962 | 0.72 | CA12 (0.38) | TSHRLMNAFNTAFNTBPGGT1B | |
| SCHEMBL10431763 | 0.71 | BCHE (0.44) | BCHENMT2NMT1SIGMAR1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212550-A2 | Substituted dipeptide amides | G.D. Searle & Co. (US) | 1987-03-04 | — | — | EP | disclosed |