Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 3/20 | 0.37 |
| ▸ | FNTB | P49356 | 3/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11497983 | 1.00 | EPHX1 (0.40) | EPHX1CA12CA9NOD1DPP7 | |
| SCHEMBL18737750 | 0.87 | NOD1 (0.39) | EPHX1NOD1DPP7FNTAFNTB | |
| SCHEMBL1147839 | 0.85 | NOD1 (0.49) | CA12CA9NOD1FNTAFNTB | |
| SCHEMBL303334 | 0.85 | NOD1 (0.49) | CA12CA9NOD1FNTAFNTB | |
| SCHEMBL303333 | 0.85 | NOD1 (0.49) | CA12CA9NOD1FNTAFNTB | |
| SCHEMBL25411986 | 0.84 | NOD1 (0.51) | NOD1FNTAFNTBPGGT1B | |
| SCHEMBL5087530 | 0.84 | NOD1 (0.51) | NOD1FNTAFNTBPGGT1B | |
| SCHEMBL7765496 | 0.84 | NOD1 (0.51) | NOD1FNTAFNTBPGGT1B | |
| SCHEMBL9341319 | 0.84 | NOD1 (0.51) | NOD1FNTAFNTBPGGT1B | |
| SCHEMBL462399 | 0.84 | NOD1 (0.48) | CA12CA9NOD1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985665-B1 | Process for the preparation of 3-amino-2-oxo-pyrrolidines, intermediates and use thereof | DEGUSSA (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-6156908-A | Procedure for the manufacture of 3-amino-2-oxo-pyrrolidines, new intermediates and their use | ROHM GESELLSCHAFT, GMBH (DE) | 2000-12-05 | — | — | US | disclosed |
| EP-0985665-A1 | Process for the preparation of 3-amino-2-oxo-pyrrolidines, intermediates and use thereof | Degussa-Hüls Aktiengesellschaft (DE) | 2000-03-15 | — | — | EP | disclosed |
| US-4216225-A | ANTIULCER AGENTS | KOWA COMPANY, LTD. (JP) | 1980-08-05 | — | — | US | disclosed |