Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13533666 | 0.87 | TSHR (0.67) | TSHRHPGDTP53CHRM2CHRM4 | |
| SCHEMBL13533665 | 0.87 | TSHR (0.67) | TSHRHPGDTP53CHRM2CHRM4 | |
| SCHEMBL6988742 | 0.87 | TSHR (0.67) | TSHRHPGDTP53CHRM2CHRM4 | |
| SCHEMBL3265469 | 0.82 | BRD4 (0.49) | TSHRHPGDBRD4MEN1KMT2A | |
| SCHEMBL11471890 | 0.79 | HPGD (0.73) | TSHRHPGDTP53CHRM2CHRM4 | |
| SCHEMBL11472575 | 0.79 | TSHR (0.69) | TSHRHPGDTP53CHRM2CHRM4 | |
| SCHEMBL10762307 | 0.79 | HPGD (0.69) | TSHRHPGDTP53CHRM2CHRM4 | |
| SCHEMBL2958047 | 0.79 | TSHR (0.69) | TSHRHPGDTP53CHRM2CHRM4 | |
| SCHEMBL13532862 | 0.79 | HPGD (0.69) | TSHRHPGDTP53CHRM2CHRM4 | |
| SCHEMBL16033027 | 0.78 | HPGD (1.00) | TSHRHPGDTP53CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699918-A | ANTICOAGULANTS, ANTIARRHYTHMIA AGENTS | LABORATOIRES JACQUES LOGEAIS (FR) | 1987-10-13 | — | — | US | disclosed |
| US-4556674-A | ANTICOAGULANTS, ANTIARRHYTHMIA AGENTS | LABORATOIRES JACQUES LOGEAIS (FR) | 1985-12-03 | — | — | US | disclosed |