SCHEMBL10761122

SCHEMBL10761122

CCCC[C@H]1CC[C@H]([C@H]2CC[C@H](c3ccc(OCC)cc3)CC2)CC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.43
CYP2C9 P11712 4/20 0.43
MAPT P10636 2/20 0.41
MEN1 O00255 2/20 0.41
MAPK1 P28482 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
HRH3 Q9Y5N1 2/20 0.40
NQO1 P15559 1/20 0.40
ESR2 Q92731 1/20 0.39
SPHK1 Q9NYA1 1/20 0.38
DRD2 P14416 1/20 0.38
CRBN Q96SW2 1/20 0.37
NPC1 O15118 2/20 0.37
CYP1A2 P05177 1/20 0.37
GAA P10253 1/20 0.37
CYP2D6 P10635 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10761128 1.00 RAB9A (0.43) RAB9ACYP2C9MAPTMEN1MAPK1
SCHEMBL10910209 0.96 RAB9A (0.42) RAB9ACYP2C9MAPTMEN1MAPK1
SCHEMBL10910213 0.96 RAB9A (0.42) RAB9ACYP2C9MAPTMEN1MAPK1
SCHEMBL9626505 0.96 RAB9A (0.46) RAB9ACYP2C9MAPTMEN1MAPK1
SCHEMBL9626500 0.96 RAB9A (0.46) RAB9ACYP2C9MAPTMEN1MAPK1
SCHEMBL10767762 0.94 SPHK1 (0.42) RAB9ACYP2C9MAPTMEN1MAPK1
SCHEMBL10767763 0.94 SPHK1 (0.42) RAB9ACYP2C9MAPTMEN1MAPK1
SCHEMBL10763505 0.93 RAB9A (0.50) RAB9ACYP2C9MAPTMEN1MAPK1
SCHEMBL10763512 0.93 RAB9A (0.50) RAB9ACYP2C9MAPTMEN1MAPK1
SCHEMBL11285546 0.91 RAB9A (0.43) RAB9ACYP2C9MAPTMEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0094487-B1 HYDROTERPHENYLS, THEIR PREPARATION AND THEIR USE IN DIELECTRIC LIQUID CRYSTAL MATERIAL MERCK PATENT GmbH (DE) 1987-09-09 EP disclosed
US-4620938-A Hydroterphenyls MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-11-04 US disclosed
EP-0094487-A1 Hydroterphenyls, their preparation and their use in dielectric liquid crystal material MERCK PATENT GmbH (DE) 1983-11-23 EP disclosed