Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Fluoride Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1955641 | 0.97 | LMNA (0.33) | LMNA | |
| Fluoride Ion SCHEMBL1955460 | 0.97 | LMNA (0.33) | LMNA | |
| Bromide SCHEMBL1030758 | 0.90 | LMNA (0.33) | LMNA | |
| Hydrochloric Acid SCHEMBL1030334 | 0.90 | LMNA (0.33) | LMNA | |
| Bromide SCHEMBL1030780 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL1027793 | 0.75 | — | — | |
| Bromide SCHEMBL1028049 | 0.75 | — | — | |
| SCHEMBL16469013 | 0.64 | — | — | |
| SCHEMBL83493 | 0.64 | — | — | |
| Water SCHEMBL9684502 | 0.60 | LMNA (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2397475-B1 | 4, 4' disubstituted 4H-cyclopentadithiophene and new methods for synthesising the same | IMEC (BE) | 2014-11-12 | — | — | EP | disclosed |
| EP-2509972-A1 | POLYMERS COMPRISING 3 -SUBSTITUTED THIOPHENE MOIETIES AS ACTIVE LAYERS FOR SOLAR CELLS | IMEC (BE) | 2012-10-17 | — | — | EP | disclosed |
| EP-2307398-B1 | POLYMERISABLE COMPOUNDS FOR MAKING OPTO-ELECTRONIC DEVICES | IMEC (BE) | 2012-09-05 | — | — | EP | disclosed |
| EP-2397475-A1 | 4, 4' disubstituted 4H-cyclopentadithiophene and new methods for synthesising the same | IMEC (BE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2011069554-A1 | POLYMERS COMPRISING 3 -SUBSTITUTED THIOPHENE MOIETIES AS ACTIVE LAYERS FOR SOLAR CELLS | IMEC (BE) | 2011-06-16 | — | — | WO | disclosed |
| EP-2307398-A1 | POLYMERISABLE COMPOUNDS FOR MAKING OPTO-ELECTRONIC DEVICES | IMEC (BE) | 2011-04-13 | — | — | EP | disclosed |
| EP-1757613-B1 | Multicoordinated metal complexes for use in metathesis reactions | TELENE SAS (FR) | 2011-01-19 | — | — | EP | disclosed |
| WO-2010000504-A1 | POLYMERISABLE COMPOUNDS FOR MAKING OPTO-ELECTRONIC DEVICES | INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (BE) | 2010-01-07 | — | — | WO | disclosed |
| US-20080293905-A9 | MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS | RIMTEC CORPORATION (JP) | 2008-11-27 | — | — | US | disclosed |
| WO-2007022945-A2 | MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS | VIACATT N.V. (BE) | 2007-03-01 | — | — | WO | disclosed |
| EP-1757613-A1 | Multicoordinated metal complexes for use in metathesis reactions | Viacatt N.V. (BE) | 2007-02-28 | — | — | EP | disclosed |
| US-20070043188-A1 | MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS | TELENE S.A.S. (FR) | 2007-02-22 | — | — | US | disclosed |