SCHEMBL1076185

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1074527	0.88	P2RX1 (0.45)	P2RX1KMT2AATMALOX15ALDH1A1
	SCHEMBL1023074	0.85	P2RX1 (0.50)	P2RX1KMT2AATMRXFP1JAK2
	SCHEMBL1025816	0.84	P2RX1 (0.51)	P2RX1KMT2AATMALOX15NPSR1
	SCHEMBL1023981	0.84	P2RX1 (0.51)	P2RX1KMT2AATMALOX15MAPT
	SCHEMBL1023141	0.83	P2RX1 (0.48)	P2RX1KMT2AATMMAPTRXFP1
	SCHEMBL1027316	0.83	P2RX1 (0.50)	P2RX1KMT2AATMRXFP1JAK2
	SCHEMBL1025783	0.82	KMT2A (0.48)	P2RX1KMT2AATMMAPTHTT
	SCHEMBL1025853	0.80	P2RX1 (0.45)	P2RX1KMT2AATMALDH1A1MAPT
	SCHEMBL1555009	0.79	GSK3B (0.48)	P2RX1KMT2AATMMAPTRXFP1
	SCHEMBL1026009	0.78	KDR (0.55)	KMT2AMAPTHTTRXFP1GSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.