Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 17/20 | 0.62 |
| ▸ | ESR1 | P03372 | 6/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10894056 | 1.00 | ESR2 (0.62) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL10762150 | 1.00 | ESR2 (0.62) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL5478613 | 0.94 | ESR2 (0.69) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL8568671 | 0.94 | ESR2 (0.69) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL18257846 | 0.88 | ESR2 (0.73) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL18257844 | 0.88 | ESR2 (0.73) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL5116401 | 0.86 | ESR2 (0.65) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL8370024 | 0.86 | ESR2 (0.65) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL8370026 | 0.86 | ESR2 (0.65) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL6452824 | 0.85 | ESR2 (0.53) | ESR2ESR1CYP2C9CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094487-B1 | HYDROTERPHENYLS, THEIR PREPARATION AND THEIR USE IN DIELECTRIC LIQUID CRYSTAL MATERIAL | MERCK PATENT GmbH (DE) | 1987-09-09 | — | — | EP | disclosed |
| US-4620938-A | Hydroterphenyls | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-11-04 | — | — | US | disclosed |
| EP-0084974-B1 | CARBOCYCLIC COMPOUNDS WITH LIQUID-CRYSTAL PROPERTIES | Chisso Corporation (JP) | 1986-04-02 | — | — | EP | disclosed |
| US-4477369-A | New high temperature liquid-crystalline substances consisting of 4 or 5 six-member-rings and liquid-crystalline compositions containing same | CHISSO CORPORATION (JP) | 1984-10-16 | — | — | US | disclosed |
| EP-0094487-A1 | Hydroterphenyls, their preparation and their use in dielectric liquid crystal material | MERCK PATENT GmbH (DE) | 1983-11-23 | — | — | EP | disclosed |
| EP-0084974-A1 | Carbocyclic compounds with liquid-crystal properties | Chisso Corporation (JP) | 1983-08-03 | — | — | EP | disclosed |